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Colloidal Gold. - Bright Star Apothecary Complimentary Integrative & Alternative Medicine at Dragonfly Kingdom International Service Agency

Posted on June 22, 2021 at 8:00 AM Comments comments (0)
Colloidal gold is a suspension of gold particles in a fluid. In ancient times, it was originally used as a method of staining glass. It has also been used in Hindu Chemistry for various potions. In 1842, John Herschel invented a photographic process that used gold to record images on paper. This was known as Chrysotype, from the Greek word for gold. As you can see, gold has been used throughout centuries for many things.

The use of gold for medicinal and healing purposes came from Alexandria, Egypt. The Egyptians ingested gold for mental, bodily and spiritual purification. Gold has also been used to reduce dependency on alcohol, caffeine, nicotine, and carbohydrates. Here at Purest Colloids, we believe in a better and healthier life. That is why we offer colloidal gold and other colloidal metals. We want you to feel your very best and life a life with the minerals and supplements you need to live healthy every day.

We are a New Jersey based company who offers you many colloidal gold products. We are an exclusive worldwide producer of Mesocolloids. We believe in living the life you always wanted and we are here to help you do that with the availability of minerals and supplements that your body does not necessarily get every day. We engage in the research and manufacture of high quality nanoparticle metal colloids. Many years of research have gone into the development of the processes used to make these colloidal products. Our research and development is ongoing in order to keep our products on the forefront of quality and effectiveness.




Effects of Meditation and Music-Listening on Blood Biomarkers of Cellular Aging and Alzheimer's Disease. - Dragonfly Kingdom Library/Spiritual Sports Medicine & Nutrition

Posted on June 22, 2021 at 7:55 AM Comments comments (0)

Abstract

Background: Telomere length (TL), telomerase activity (TA), and plasma amyloid-β (Aβ) levels have emerged as possible predictors of cognitive decline and dementia.

 

Objective: To assess the: 1) effects of two 12-week relaxation programs on TL, TA, and Aβ levels in adults with subjective cognitive decline; and 2) relationship of biomarker changes to those in cognitive function, psychosocial status, and quality of life (QOL).

 

Methods: Participants were randomized to a 12-week Kirtan Kriya meditation (KK) or music listening (ML) program and asked to practice 12 minutes/day. Plasma Aβ(38/40/42) and peripheral blood mononuclear cell TL and TA were measured at baseline and 3 months. Cognition, stress, sleep, mood, and QOL were assessed at baseline, 3 months, and 6 months.




 

Results: Baseline blood samples were available for 53 participants (25 KK, 28 ML). The KK group showed significantly greater increases in Aβ40 than the ML group. TA rose in both groups, although increases were significant only among those with higher practice adherence and lower baseline TA. Changes in both TL and TA varied by their baseline values, with greater increases among participants with values ≤50th percentile (ps-interaction <0.006). Both groups improved in cognitive and psychosocial status (ps ≤0.05), with improvements in stress, mood, and QOL greater in the KK group. Rising Aβ levels were correlated with gains in cognitive function, mood, sleep, and QOL at both 3 and 6 months, associations that were particularly pronounced in the KK group. Increases in TL and TA were also correlated with improvements in certain cognitive and psychosocial measures.

 

Conclusion: Practice of simple mind-body therapies may alter plasma Aβ levels, TL, and TA. Biomarker increases were associated with improvements in cognitive function, sleep, mood, and QOL, suggesting potential functional relationships.

 

Keywords: Alzheimer’s disease; cognition; memory complaints; mind-body therapy; mood; plasma amyloid-β; quality of life; sleep; subjective cognitive impairment; telomerase; telomeres.



Indexed for NIH Pubmed by Dragonfly Kingdom Library 


https://pubmed.ncbi.nlm.nih.gov/30320574/

Spiritual Fitness: A New Dimension in Alzheimer's Disease Prevention. - Dragonfly Kingdom Library/Spiritual Sports Medicine & Nutrition

Posted on June 22, 2021 at 7:50 AM Comments comments (0)

Abstract

Background: Religious and spiritual interventions may have an effect on Alzheimer's disease prevention. Kirtan Kriya meditation has been shown to mitigate the deleterious effects of chronic stress on cognition, reverse memory loss, and create psychological and spiritual wellbeing, which may reduce multiple drivers of Alzheimer's disease risk.

 

Objective: To detail a new concept in medicine called Spiritual Fitness, a merging of stress reduction, basic wellbeing, and psycho/spiritual wellbeing to prevent Alzheimer's disease.

 

Methods: The literature on the topics mentioned above is described, including an in-depth discussion on why and how each are critical to advancing the future of Alzheimer's disease prevention. The many negative effects of chronic stress, and the benefits of Kirtan Kriya, are reviewed. The four pillars of basic wellbeing, six practical aspects of psychological wellbeing, and the four new non-sectarian features of spiritual fitness are then disclosed. Moreover, instructions on practicing Kirtan Kriya are offered in the Supplementary Material.




 

Conclusion: Religious and spiritual practices, including Kirtan Kriya, are crucial components in the development of enhanced cognition and well-being, which may help prevent and, in some cases, reverse cognitive decline. The key point of this review is that making a commitment to live a brain longevity lifestyle including spiritual fitness is a critically important way for aging Alzheimer's disease free. We hope that this article will inspire scientists, clinicians, and patients to embrace this new concept of spiritual fitness and make it a part of every multidomain program for the prevention of cognitive disability.

 

Keywords: Alzheimer’s disease prevention; kirtan kriya meditation; neurotheology; peace of mind; psychological well-being; purpose in life; spiritual fitness; spiritual well-being; spiritual/religious involvement; unlimited love 



Indexed for NIH Pubmed by Dragonfly Kingdom Library 


https://pubmed.ncbi.nlm.nih.gov/33554917/




Silver may be useful as an antimicrobial laundry additive to decontaminate healthcare laundry washed at low temperatures in domestic and industrial settings

Posted on June 20, 2021 at 10:20 AM Comments comments (0)
Silver may be useful as an antimicrobial laundry additive to decontaminate healthcare laundry washed at low temperatures in domestic and industrial settings






Abstract
Aims: To repurpose a silver-based antimicrobial textile coating product (Micro-Fresh 1911) as a dual-function antimicrobial laundry additive and textile coating.

Methods and results: Survival of Escherichia coli or Staphylococcus aureus type and clinical isolates in a domestic 40°C wash was assessed with and without soiling and biological detergent. Washing with 2% w/v silver additive (wash phase) reduced E. coli and S. aureus by 7·14-8·08 log10 and no cross-contamination was observed. Under dirty conditions, 0·5% silver additive in the rinse phase of a wash with biological detergent reduced E. coli and S. aureus by 7·98-8·40 log10 (0·00-1·42 log10 cross contamination). BS EN ISO 20645:2004 and BS EN ISO 20743:2013 methods were used to assess the antimicrobial activity of polycotton washed with 2% w/v silver additive against S. aureus and E. coli. The treated polycotton was antimicrobial against E. coli and S. aureus type and clinical isolates and remains active after at least one further wash cycle at 40 or 73°C.

Conclusions: The silver additive exhibits antimicrobial activity in a 40°C domestic wash, preventing cross contamination onto clean textiles and depositing an antimicrobial coating onto polycotton.

Significance and impact of the study: The survival of micro-organisms on healthcare uniforms during domestic laundering presents a potential risk of contaminating the home, cross-contamination of other clothing within the wash and transmitting potential pathogens back into healthcare settings via contaminated uniforms. Silver may be useful as an antimicrobial laundry additive to decontaminate healthcare laundry washed at low temperatures in domestic and industrial settings, to therefore reduce the potential risk of transmitting micro-organisms within the domestic and clinical environments.

Keywords: Escherichia coli; Staphylococcus aureus; antimicrobial textile; cross contamination; decontamination; healthcare laundry; laundry additive

Indexed for NIH Pubmed by Dragonfly Kingdom Library

These structures may provide a target for energy-based therapeutic intervention in stealth-virus-infected patients. - Dragonfly Kingdom Library

Posted on June 16, 2021 at 12:25 AM Comments comments (0)

Complex intracellular inclusions in the brain of a child with a stealth virus encephalopathy.

Martin WJ1

Author information

Experimental and Molecular Pathology, 01 Jun 2003, 74(3):197-209

DOI: 10.1016/s0014-4800(03)00038-8 PMID: 12782006

 


Abstract

Unusual pigmented intracellular inclusions are commonly seen in cultures obtained from patients infected with stealth viruses. Some of these structures may potentially provide a source of chemical energy for the infected cells to help compensate for the apparent damage to the cells' mitochondria. They have accordingly been termed alternative cellular energy pigments (ACE pigments). In keeping with this suggestion, the present paper illustrates the diversity of extraneous materials present in vacuolated, mitochondria-damaged cells seen in the brain biopsy of a child with a stealth-virus-associated encephalopathy. Many of the intracellular inclusions show highly ordered structuring, while others have a more amorphous appearance. These structures may provide a target for energy-based therapeutic intervention in stealth-virus-infected patients.





The potential contributing role of stealth virus infections in children presenting with behavioral problems needs to be addressed. - Dragonfly Kingdom Library

Posted on June 16, 2021 at 12:20 AM Comments comments (0)

An infectious illness, attributed to atypically structured cytopathic "stealth" viruses, occurred in 1996 in the Mohave Valley region of the United States. A stealth virus-infected child from this region has developed a severe noninflammatory, vacuolating (spongiform) en cephalopathy. The illness initially presented as a behavioral problem without overt neurological signs. Extensive investigations, including repeated magnetic resonance imaging, two brain biopsies, and stealth virus cultures, have helped define the disease process occurring in this child. Significant clinical benefit with apparent retardation of disease progression occurred during a 6-week course of ganciclovir therapy. The potential contributing role of stealth virus infections in children presenting with behavioral problems needs to be addressed.




Indexed for Europe PMC by Dragonfly Kingdom Library 


 https://europepmc.org/article/MED/10331961

Chronic Fatigue Syndrome (CFS): An Imprecisely Defined Infectious Disease Caused by Stealth Adapted Viruses. - Dragonfly Kingdom Library

Posted on June 16, 2021 at 12:05 AM Comments comments (0)

Chronic Fatigue Syndrome (CFS): An Imprecisely Defined Infectious Disease Caused by Stealth Adapted Viruses

W John Martin*

Institute of Progressive Medicine, South Pasadena, USA

 

Introduction

Much of the research on the chronic fatigue syndrome (CFS) is misguided for two major reasons. First, it is falsely assumed that CFS is a distinct, definable illness, which can be reliably differentiated from other neurological and psychiatric illnesses. Second, in spite of compelling evidence to the contrary, CFS is not generally regarded as an infectious illness. This review addresses these two issues and is followed by a brief discussion on stealth adapted viruses and the alternative cellular energy (ACE) pathway.

 

Diagnosis

It is clearly inappropriate that the diagnosis of CFS is being applied to severely ill, bedridden patients, as well as to outspoken, internet savvy individuals who frequently attend conferences and other public events. The core symptom for the majority of those diagnosed with CFS is a feeling of not having sufficient physical and/or mental capacity to undertake ordinary tasks, with no clear explanation as to why this limitation exists. The frustrating feeling of persisting fatigue will typically become exacerbated, with a delayed onset after even modest physical and/or mental exertion and can remain so for several days, without being relieved by sleep. Beyond the core symptom of unexplained fatigue, there are a plethora of additional clinical manifestations. To a varying extent, different CFS patients experience mental confusion with a lack of clarity in their thoughts (brain fog); inability to stay focused on a topic (attention deficit); poor memory, even forgetting the names of common everyday items; and emotional lability, expressed as periods of sadness (lack of joy); and occasionally as anxiety, anger and/or depression. CFS patients can often experience hypersensitivity to sensory inputs, leading to pain, paresthesia, photophobia, tinnitus and chemical sensitivity. The autonomic nervous system may show signs of dysregulation such as postural hypotension with tachycardia; other disorders affecting blood circulation; irritable bowel; etc. The severity of these various symptoms differs widely among patients diagnosed with CFS and can also vary markedly over time in the same individual. Unless further defined, the CFS diagnosis is largely uninformative with regards to a particular patient's illness. Furthermore, similar sets of symptoms can be present in patients with traumatic brain injuries and in patients in whom additional symptoms or laboratory test results can lead to a better defined neurological, psychiatric, or autoimmune diagnosis. Based on more questionable criteria, some patients who would otherwise be diagnosed as mild to moderate CFS are diagnosed as having depression, personality disorder, burnout, post-traumatic stress, fibromyalgia, chronic Lyme disease, Gulf War syndrome, chronic inflammatory response syndrome (CIRS), chemical sensitivity, electromagnetic sensitivity, irritable bowel syndrome, etc. According to some definitions, CFS is excluded if the patient has psychiatric symptoms, yet other definitions allow for co-morbid psychiatric diagnoses [1-6].

 

Several laboratory tests will commonly yield results in CFS patients, which are different from those in most healthy controls [7-26]. The items being tested are only loosely directed to the element of chronic fatigue. Moreover, similar abnormal results can occur in association with many other chronic illnesses in which fatigue is not a predominant feature. Emotional stress and prolonged periods of physical inactivity can potentially cause disruptions in the biochemical pathways measured in some of these assays. It has also been argued that knowing that one has an abnormal test result will simply add to further pessimism about being ill. Certain individuals seem to do better by consciously disregarding the illness concept and are more accepting of their physical and mental limitations. The diagnosis of CFS for these patients is considered counterproductive.



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Infection

Multiple lines of evidence indicate an infectious cause of CFS. The first is the occurrence of major outbreaks of CFS-related illnesses. Seventy-three outbreaks occurring between 1934 and 1990 are listed in the book The Clinical and Scientific Basis of Myalgic Encephalomyelitis - Chronic Fatigue Syndrome, edited by Dr. Byron Hyde [27]. Prominent among these outbreaks was an illness beginning in 1985 and first publicly reported in 1986, which occurred in the Lake Tahoe/Incline Village region of Nevada [28]. Two of the many unpublicized subsequent outbreaks in the US are worth noting. Dr. Donovan Anderson manages a general medical practice in Mohave Valley, Arizona, which is nearby to Needles, California. In the spring of 1996, he became aware of an acute illness which progressively affected well over a hundred of the local residents. Individuals presented with acute gastrointestinal symptoms, developing approximately a week after contact with someone with similar symptoms. Vomiting, diarrhea and abdominal pain would resolve within 1-2 weeks. Rather than the individuals regaining their prior health, most progressed to a chronic illness. This illness was characterized by severe fatigue, cognitive impairments and mood disorders [29]. The disease affecting most of these individuals was confirmed as CFS by a visiting specialist in this condition. Several patients had very severe illnesses, including dementia. A veterinarian exhibited symptoms of acute depression prior to suicide. An 8-year-old child of a symptomatic mother exhibited attention deficit hyperactivity disorder (ADHD) in second grade. He mentioned to his mother that he would see double when tired or stressed. An MRI of his brain showed fairly extensive white matter disease suggestive of a leukodystrophy, with frontal lobe predominance. A brain biopsy of the frontal lobe showed no inflammation. Rather it was pathologically described as a spongy (vacuolar) myelinopathy [30]. Based on a positive stealth virus culture (to be discussed in a later section of this article), the child was prescribed a course of ganciclovir, which provided some temporary clinical improvements. Nevertheless, he continued to deteriorate, became physically incapacitated and died approximately one-year later. Blood samples from over 50 additional patients involved in this outbreak were also cultured for evidence of infection with stealth adapted viruses. All of the tested samples gave strongly positive results. Most of the patients have remained chronically ill for over 20 years with many now being diagnosed as having fibromyalgia in addition to CFS.


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A hairdresser in Joelton, TN, realized she, her two staff members, and a number of her clients were experiencing episodes of pain that mainly affected areas of their skin, along with a feeling of general malaise and noticeably impaired thought processing. She communicated her concerns to the local health authority and to the Centers for Disease Control and Prevention (CDC). The representative from the CDC asked if she knew of additional patients. The hairdresser took the initiative of describing her illness in the local Shopper magazine. Well over 100 people from the local community responded that they were experiencing similar symptoms. As soon as the issue of a potential infectious process arose, the local health authority, on the advice from CDC, refused to engage in any further contact. This patient and several of her close associates tested positive in stealth adapted virus cultures...... 


Indexed for Journal Of Infectious Diseases & Epidemiology by Dragonfly Kingdom Library  

https://www.clinmedjournals.org/articles/jide/journal-of-infectious-diseases-and-epidemiology-jide-6-106.php?jid=jide



These findings support the concepts that stealth viruses can account for a spectrum of dysfunctional brain diseases. - Dragonfly Kingdom Library

Posted on June 15, 2021 at 11:30 AM Comments comments (0)

Abstract

A cytopathic 'stealth' virus was cultured from the cerebrospinal fluid of a patient with a bipolar psychotic disorder who developed a severe encephalopathy leading to a vegetative state. DNA sequencing of a polymerase chain reaction-amplified product from infected cultures has identified the virus as an African green monkey simian cytomegalovirus (SCMV)-related stealth virus. The virus is similar to the SCMV-related stealth virus isolated from a patient with chronic fatigue syndrome. The findings support the concepts that stealth viruses can account for a spectrum of dysfunctional brain diseases and that some of these viruses may have arisen from live polio viral vaccines.


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Indexed for NIH Pubmed by Dragonfly Kingdom Library


https://pubmed.ncbi.nlm.nih.gov/8888270/

Microbial infections in eight genomic subtypes of chronic fatigue syndrome/myalgic encephalomyelitis. - Dragonfly Kingdom Library

Posted on June 15, 2021 at 11:15 AM Comments comments (0)

Abstract

Background: The authors have previously reported genomic subtypes of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) based on expression of 88 human genes.

 

Aim: To attempt to reproduce these findings, determine the specificity of this signature to CFS/ME, and test for associations between CFS/ME subtype and infection.

 

Methods: Expression levels of 88 human genes were determined in blood of 62 new patients with idiopathic CFS/ME (according to Fukuda criteria), six patients with Q-fever-associated CFS/ME from the Birmingham Q-fever outbreak (according to Fukuda criteria), 14 patients with endogenous depression (according to DSM-IV criteria) and 29 normal blood donors.


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Results: In patients with CFS/ME, differential expression was confirmed for all 88 genes. Q-CFS/ME had similar patterns of gene expression to idiopathic CFS/ME. Gene expression in patients with endogenous depression was similar to that in the normal controls, except for upregulation of five genes (APP, CREBBP, GNAS, PDCD2 and PDCD6). Clustering of combined gene data in CFS/ME patients for this and the authors' previous study (117 CFS/ME patients) revealed genomic subtypes with distinct differences in SF36 scores, clinical phenotypes, severity and geographical distribution. Antibody testing for Epstein-Barr virus, enterovirus, Coxiella burnetii and parvovirus B19 revealed evidence of subtype-specific relationships for Epstein-Barr virus and enterovirus, the two most common infectious triggers of CFS/ME.

 

Conclusions: This study confirms the involvement of these genes in CFS/ME 


Indexed for NIH Pubmed by Dragonfly Kingdom Library 


https://pubmed.ncbi.nlm.nih.gov/19955554/



In some cases of violence and other criminal behavior, this can be a consequence of central nervous system infection. - Dragonfly Kingdom Library

Posted on June 15, 2021 at 10:55 AM Comments comments (0)

Abstract

Infections of the central nervous system can damage the brain and cause abnormal behavior. In this article, the authors examine how behavior is affected by damage to different parts of the brain. They then focus on damage caused by specific infections of the brain and how these can result in abnormal behavior with legal consequences.


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Examples of such infections include neurosyphilis, encephalitis lethargica, herpes simplex encephalitis, and various other viral encephalitides, both acute and chronic. The AIDS dementia complex, which results from HIV infection of the brain, causes behavioral abnormalities in addition to motor and cognitive impairments. In some cases of violence and other criminal behavior, this can be a consequence of central nervous system infection, and the authors suggest that criminal sanctions in such events are inappropriate in the absence of volitional criminal intent.



Indexed for NIH Pubmed by Dragonfly Kingdom Library 


https://pubmed.ncbi.nlm.nih.gov/14584527/

Mainstream neurologists and psychiatrists have largely refrained from serious consideration of a virus cause of common brain diseases. This article exposes a weakness in this argument by describing the process of stealth adaptation of viruses. - Dra

Posted on June 15, 2021 at 10:35 AM Comments comments (0)


eISSN: 2373-6410

 

Neurology & Stroke

 

 


 

Stealth Adapted Viruses – Possible Drivers of Major Neuropsychiatric Illnesses Including Alzheimer’s Disease

W John Martin

Institute of Progressive Medicine, South Pasadena, USA

 

Correspondence: W John Martin, Institute of Progressive Medicine, 1634 Spruce Street, South Pasadena, CA 913, USA, Tel 626-616-2868

 

Received: May 22, 2015 | Published: June 22, 2015

 

Citation: Martin WJ (2015) Stealth Adapted Viruses – Possible Drivers of Major Neuropsychiatric Illnesses Including Alzheimer’s Disease. J Neurol Stroke 2(3): 00057. DOI: 10.15406/jnsk.2015.02.00057

 


 

Abstract

Mainstream neurologists and psychiatrists have largely refrained from serious consideration of a virus cause of common brain diseases. This is mainly because of the general lack of any accompanying immune system stimulated inflammatory reaction within the brain. This article exposes a weakness in this argument by describing the process of “stealth adaptation” of viruses. Deletion or mutation of relatively few virus components can result in derivative viruses, which are no longer effectively recognized by the cellular immune system. Consequently, there is no triggering of the inflammatory response. Furthermore, the brain is uniquely susceptible to symptomatic illness caused by stealth adapted viruses. An understanding of stealth adaptation greatly expands the potential scope of viral illnesses. It also underscores the value of using virus cultures as a diagnostic tool and of taking appropriate measures to avoid transmission of infection. More importantly, therapeutic measures are available for suppressing both stealth adapted and conventional virus infections through enhancement of the alternative cellular energy (ACE) pathway. Such measures are available for clinical evaluation in treating many of the major illnesses affecting the brain, including Alzheimer’s disease.

 

Keywords: Alzheimer’s disease; Neurology; Psychiatry; Cellular immunity; Immune evasion; Inflammation; Alternative cellular energy; ACE; Stealth adapted viruses; Herpes simplex virus; HSV; EnerceuticalsTM; KELEA; CFS; Chronic fatigue syndrome; Dementia; Encephalopathy

 

Abbreviations:

KELEA: Kinetic Energy Limiting Electrostatic Attraction; ACE: Alternative Cellular Energy; CFS: Chronic Fatigue Syndrome; CPE: Cytopathic Effect; HSV: Herpes Simplex Virus; SCMV: African Green Monkey Simian Cytomegalovirus; HCMV: Human Cytomegalovirus; CTL: Cytotoxic T Lymphocytes; CSF: Cerebrospinal Fluid; CPE: Cytopathic Effect; ALS: Amyotrophic Lateral Sclerosis; ACE: Alternative Cellular Energy; UV: Ultraviolet; ICE: Insufficiency of Cellular Energy 



Introduction

With the possible exception of cancer, diseases of the brain comprise most of the worst feared human aliments. Whether it is the increasing likelihood of autism occurring in children [1]; or Alzheimer’s disease occurring in the elderly [2], the current medical paradigms are failing to provide effective answers. Nor has significant progress been made in addressing many other tragic illnesses, such as schizophrenia, bipolar psychosis, Parkinson’s disease and amyotrophic lateral sclerosis (ALS). Society is further challenged by a range of somewhat less severe but still disabling illnesses, including chronic fatigue syndrome (CFS), fibromyalgia, depression, drug addiction, criminal behaviors and intellectual impairments affecting both learning and work performances.

 

Various investigators have suggested a possible infectious origin of several of the aforementioned neuropsychiatric illnesses [3-11]. Because of the absence of noticeable inflammation, however, it is usually argued that if infectious agents are indeed involved, their effects must be indirect and quite possibly delayed. For example, common infections occurring during pregnancy can clearly lead to elevated levels of various cytokines as part of the immune response. There are supporting data that maternal cytokines may significantly inhibit normal fetal brain development, with potential later life consequences [12-14]. Other researchers have suggested that certain infectious agents might potentially trigger the production of antibodies, which cross-react with neuronal components, thereby interfering with normal brain function. Such self-reacting antibodies may continue to form as part of an ongoing autoimmune process [15-17]. None of these scenarios envisions viruses as the direct cause of ongoing cellular injury...........


Indexed for Medcrave by Dragonfly Kingdom Library

https://medcraveonline.com/JNSK/stealth-adapted-viruses-ndash-possible-drivers-of-major-neuropsychiatric-illnesses-including-alzheimerrsquos-disease.html

HERV-W ENV was highly expressed in the leukocytes of COVID-19 patients but not in those of healthy donors. - Dragonfly Kingdom Library

Posted on June 15, 2021 at 9:50 AM Comments comments (0)

 

 

Abstract

Background

Despite an impressive effort in clinical research, no standard therapeutic approach for coronavirus disease 2019 (COVID-19) patients has been established, highlighting the need to identify early biomarkers for predicting disease progression and new therapeutic interventions for patient management. The present study aimed to evaluate the involvement of the human endogenous retrovirus -W envelope (HERV-W ENV) in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection considering recent findings that HERVs are activated in response to infectious agents and lead to various immunopathological effects. We analysed HERV-W ENV expression in blood cells of COVID-19 patients in correlation with clinical characteristics and have discussed its potential role in the outcome of the disease.

Methods

We analysed HERV-W ENV expression in blood samples of COVID-19 patients and healthy donors by flow cytometry and quantitative reverse transcriptase PCR analysis, and evaluated its correlation with clinical signs, inflammatory markers, cytokine expression, and disease progression.





 

Findings

HERV-W ENV was highly expressed in the leukocytes of COVID-19 patients but not in those of healthy donors. Its expression correlated with the markers of T-cell differentiation and exhaustion and blood cytokine levels. The percentage of HERV-W ENV-positive lymphocytes correlated with inflammatory markers and pneumonia severity in COVID-19 patients. Notably, HERV-W ENV expression reflects the respiratory outcome of patients during hospitalization.

Interpretation

Given the known immuno- and neuro-pathogenicity of HERV-W ENV protein, it could promote certain pathogenic features of COVID-19 and therefore serve as a biomarker to predict clinical progression of disease and open to further studies for therapeutic intervention.



Indexed for The Lancet by Dragonfly Kingdom Library 


https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(21)00134-1/fulltext

Etheric biology: Recent studies suggest that ACE pigments may also capture etheric energy. ACE activation can also assist in the systemic healing of infections caused by conventional viruses. - Dragonfly Kingdom Library/Spiritual Sports Medicine & Nutriti

Posted on June 14, 2021 at 12:00 AM Comments comments (0)

Abstract

Several observations made during the course of studies on stealth-adapted viruses are explainable by a pervasive, energy-rich, ether environment. Activation of an alternative cellular energy (ACE) pathway provides stealth virus damaged cells with a repair mechanism that is independent of the cellular immune response. ACE activation can also assist in the systemic healing of infections caused by conventional viruses such as Herpes simplex virus, Herpes zoster virus and human papillomavirus. ACE pigments convert conventional forms of physical energies into a biological cell healing energy, the nature of which is still uncertain.

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More recent studies suggest that ACE pigments may also capture etheric energy. In addition to cellular repair, ACE pigment activation can lead to the biogenesis of lipid-like chemical structures. ACE pigment and virus culture healing activities were also seen with several natural products, including a homeopathic formulation. A colloidal silver solution appeared to facilitate the transmission of ACE and to enhance its biosynthetic activity. These results open a window into a greater understanding of a fundamental force of nature of potential therapeutic importance.


Indexed for NIH Pubmed by Dragonfly Kingdom Library


https://pubmed.ncbi.nlm.nih.gov/15893748/

Origins of Life? Study Shows Adding UV Light Helps Form 'Missing G' of RNA Building Blocks. - Dragonfly Kingdom Library

Posted on June 13, 2021 at 11:40 AM Comments comments (0)



For scientists attempting to understand how the building blocks of RNA originated on Earth, guanine has proven to be a particular challenge. By adding UV light to a model prebiotic reaction, researchers have discovered a route by which guanine could have been formed.



https://www.nsf.gov/news/news_summ.jsp?cntn_id=117226

Ultraviolet Irradiation of Blood: The Cure That Time Forgot? DNA damage in host cells can be rapidly repaired by DNA repair enzymes. - Dragonfly Kingdom Library/Bright Star Apothecary Complimentary Integrative & Alternative Medicine

Posted on June 13, 2021 at 11:30 AM Comments comments (0)

HHS Public Access

Ultraviolet Irradiation of Blood: “The Cure That Time Forgot”?

Michael R. Hamblin

 


 

Abstract

Ultraviolet blood irradiation (UBI) was extensively used in the 1940s and 1950s to treat many diseases including septicemia, pneumonia, tuberculosis, arthritis, asthma and even poliomyelitis. The early studies were carried out by several physicians in USA and published in the American Journal of Surgery. However with the development of antibiotics, UBI use declined and it has now been called “the cure that time forgot”. Later studies were mostly performed by Russian workers and in other Eastern countries and the modern view in Western countries is that UBI remains highly controversial.


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This chapter discusses the potential of UBI as an alternative approach to current methods used to treat infections, as an immune-modulating therapy and as a method for normalizing blood parameters. No resistance of microorganisms to UV irradiation has been reported, and multi- antibiotic resistant strains are as susceptible as their wild-type counterparts. Low and mild doses of UV kill microorganisms by damaging the DNA, while any DNA damage in host cells can be rapidly repaired by DNA repair enzymes. However the use of UBI to treat septicemia cannot be solely due to UV-mediated killing of bacteria in the blood-stream, as only 5–7% of blood volume needs to be treated with UV to produce the optimum benefit. UBI may enhance the phagocytic capacity of various phagocytic cells (neutrophils and dendritic cells), inhibit lymphocytes, and oxidize blood lipids. The oxidative nature of UBI may have mechanisms in common with ozone therapy and other oxygen therapies. There may be some similarities to extracorporeal photopheresis (ECP) using psoralens and UVA irradiation. However there are differences between UBI and ECP in that UBI tends to stimulate the immune system, while ECP tends to be immunosuppressive. With the recent emergence of bacteria that are resistant to all known antibiotics, UBI should be more investigated as an alternative approach to infections, and as an immune-modulating therapy.

 

Keywords: Ultraviolet C, Knott hemo-irradiator, UBI, DNA repair, Blood cells, Antigen-presenting cells, Infections, Cytokines......


Indexed for NIH by Dragonfly Kingdom Library


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122858/

Enhancing the Alternative Cellular Energy (ACE) Pathway with KELEA Activated Water as Therapy for Infectious Diseases. - Dragonfly Kingdom Library/Spiritual Sports Medicine & Nutrition

Posted on June 13, 2021 at 10:05 AM Comments comments (0)

Abstract

Many infectious diseases have yet to be conquered by modern medicine. This is generally attributed to both a failure of the immune system and the lack of an effective anti-microbial pharmaceutical. Infections can be regarded as a competitive process between the microbe and the host for cellular energy-generated resources. Cells obtain energy not only from the metabolism of food but also from the alternative cellular energy (ACE) pathway. This pathway utilizes an environmental force termed KELEA (kinetic energy limiting electrostatic attraction), which provides an added kinetic/chemical energy to the body’s fluids.


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The ACE pathway can be enhanced through the use of KELEA activated water, which is currently available under different names from several sources. Enhancing the body’s ACE pathway, including the use of a wearable waterceutical™ , provides a novel means of potentially increasing the body’s resistance against all infectious diseases.

 

Keywords: ACE Pathway; Alternative Cellular Energy; KELEA Activated Water; Waterceutical; Stealth Adapted Viruses 


Indexed for NIH Pubmed by Dragonfly Kingdom Library

https://pubmed.ncbi.nlm.nih.gov/32066365/



Cells obtain energy not only from the metabolism of food but also from the alternative cellular energy (ACE) pathway. This pathway utilizes an environmental force. - Dragonfly Kingdom Library/Bright Star Apothecary Complimentary Integrative & Alternative

Posted on June 13, 2021 at 10:00 AM Comments comments (0)

Cells obtain energy not only from the metabolism of food but also from the alternative cellular energy (ACE) pathway. This pathway utilizes an environmental force termed KELEA (kinetic energy limiting electrostatic attraction), which provides an added kinetic/chemical energy to the body’s fluids. The ACE pathway can be enhanced through the use of KELEA activated water, which is currently available under different names from several sources.


Indexed for Bentham Science Publishers/NIH Pubmed by Dragonfly Kingdom Library


Imbalance of a positive charge: Structurally Observed Electrostatic Features of the COVID-19 Coronavirus-Related Experimental Structures inside Protein Data Bank: A Brief Update. - Dragonfly Kingdom Library

Posted on June 13, 2021 at 8:30 AM Comments comments (0)

Since the Coronavirus disease (COVID-19) outbreak at the end of 2019, the past two month has seen an acceleration both in and outside China in the R&D of the diagnostics, vaccines and therapeutics for this novel coronavirus. As one of the molecular forces that determine protein structure, electrostatic effects dominate many aspects of protein behaviour and biological function. Thus, incorporating currently available experimental structures related to COVID-19, this article reports a simple python-based analysis tool and a LaTeX-based editing tool to extract and summarize the electrostatic features from experimentally determined structures, to strengthen our understanding of COVID-19's structure and function and to facilitate machine-learning and structure-based computational design of its neutralizing antibodies and/or small molecule(s) as potential therapeutic candidates. Finally, this article puts forward a brief update of the structurally observed electrostatic features of the COVID-19 coronavirus


Li, W. Structurally Observed Electrostatic Features of the COVID-19 Coronavirus-Related Experimental Structures inside Protein Data Bank: A Brief Update. Preprints 2020, 2020030081 (doi: 10.20944/preprints202003.0081.v1).


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The charged amino acids in the spike protein of SARS-CoV-2 exhibit some specific distribution. In the RBD region of the S1 unit the positive charge dominates in the protein interior and the negative charge prevails on the surface exposed towards ACE2 receptor. The charged amino acids in the S2 region preceding heptad repeats of the spike protein of SARS-CoV-2, exhibit a central concentration, and the imbalance of a positive charge. The idea that both distributions of charged amino acids may, in an electrostatic manner, facilitate the coronavirus infection of the cell is presented. An evaluation of the virus-receptor binding energy, by docking the peptide resembling the human receptor site to the virus RBD, and the estimation of electromechanical deformation of the cell membrane by S2 during the prefusion process were included. Possible prevention of viral infection is suggested.

Keywords: coronavirus, COVID-19, SARS-CoV-2, fusion, amino acids, electric field, charge, electrostatic potential, anions, vitamin C


Government data shows rising OOP spending for consumers, but excludes some types of health-related items and services that add significantly to the total amount and consumer share of spending. Examples include nutritional supplements and complementary

Posted on June 8, 2021 at 8:35 AM Comments comments (0)

Government data shows rising OOP spending for

consumers, but excludes some types of health-related items

and services that add significantly to the total amount and

consumer share of spending. Examples include nutritional

supplements and complementary and alternative medicine.



https://www2.deloitte.com/content/dam/Deloitte/us/Documents/life-sciences-health-care/us-lchs-dig-deep-hidden-costs-112414.pdf