International Music Therapy / DJ Services - Muscle/Fitness - New Media Network - Career Development - MetaPhysical Library - Portal - Spiritual Evolution 


Shaktipat & Subtle Power of Spiritual Energy. Intrinsic need for spiritual energy for the expansion of consciousness from teacher or guru to the student. - Dragonfly Kingdom Library

Posted on April 10, 2021 at 8:05 AM Comments comments (0)


While talking about the role played by a teacher, Master Choa Kok Sui said that the Guru is like a transformer who “brings down high spiritual energy to the level your subtle bodies can handle”. So, what is this spiritual energy?


Spiritual energy has often been referred to as Chi or Qi energy which is basically the life-force that permeates and energizes everything. Various techniques have been formulated to channel this energy and to use it for healing. Spiritual energy is therefore best regarded as a powerful force that is not bound by any confinement.


Grand Master Choa Kok Sui stated the intrinsic need for spiritual energy for the expansion of consciousness. Spiritual energy is also what makes it possible to travel into the inner realms of the spiritual world. The attainment of stillness and awareness is not enough to fuel spiritual growth. Without spiritual energy, the consciousness cannot grow and expansion is stalled.


Shaktipat is a Sanskrit term that is basically a conjugation of the two terms, “shakti”, meaning power or energy and “pat”, meaning to fall or descend. Shaktipat is therefore the “transference of tremendous spiritual energy” from the teacher or guru to the student. This enables the consciousness of the disciple to be able to traverse through the different levels of the inner world. This process of energy-transfer is referred to as spiritual initiation in various esoteric books that are available today.


To explain the immense power of spiritual energy and the process of it being transformed and transferred, Grand Master Choa Kok Sui use a very interesting analogy:-


“You have 110-volt plugs. If you put your equipment directly into the transfer outlet, it gets destroyed. If you put it directly into the power source, it gets really destroyed. So from the power source it gets stepped down, stepped down, stepped down until the appliances in your home can handle it. The same thing here; there is a stepping-down process. One of the functions of the teacher is to step down the energy so that the higher soul and the incarnated soul can handle it”.


What Master Choa Kok Sui explained in such simple terms is proof of how amazing a teacher he was to be able to relate to his students such difficult concepts with such ease.


The entire universe is a web of energy and this energy is emanated at all times, through all things. When we invoke or meditate, there is a descent of Divine energy into our beings. However, to be able to handle huge quantities of spiritual energy, one must develop his/her physical bodies. The development of our spiritual or energy body is not possible without the development of our tangible physical forms. Spiritual practices are all aimed at gaining mastery over spiritual energy which would then enable an individual to transform this energy and utilize its vast potential.

Indexed for World Pranic Healing by Dragonfly Kingdom Library


The (New) Natural Science of Inclusive Flow. - Dragonfly Kingdom Library

Posted on April 10, 2021 at 8:00 AM Comments comments (0)


By Alan Rayner


Fundamental Principles


Matter that is devoid of space would be dimensionless (without size or shape); space without matter would be formless.

Therefore matter and space, as natural presences, are included in each other; they are not mutually exclusive opposites.

This is only possible if matter is made from energy swirling around particular spatial localities. These localities may be central points or straight or curved channels or interfaces. Together, the swirls of energy and the spatial localities combine to create tangible forms that exist for variable periods of time within particular places. Material bodies can hence be thought of as dynamic localities of ‘place-time’. Since they are products of natural energy flow, they can also be thought of as ‘flow-forms’.

Material form is intrinsically dynamic - a product of natural flow, which arises from the relationship between space and energy. Space plays a receptive, invitingrole and energy plays a responsive, informative role in this relationship, which distinguishes material bodies from one another and their surroundings, but does not isolate them as definitively bounded objects.


So matter both inhabits and incorporates space. It does not occupy or displace space. Space is a natural intangible – and therefore frictionless – presence that cannot be cut by anything or be excluded from anything.


Hence there is no such thing as instantaneous, independent material existence, isolated from space, time or energy.

Mechanisms of inter-action between material bodies are derived from intrinsic energy flux. They are not enforced from outside.

All natural geometrical forms either are, or are derived from circular or spherical form – not rectilinear form.

Natural numerical identities are energetic inclusions of zero-dimensional points in infinite space, not static material figures set aside from space.



Actual sensory human experience tells us:-


Natural material bodies are distinguishable from one another and their surroundings.

Natural material bodies can move, be moved, reconfigure, heat up, cool down, reflect or absorb light, melt, boil, solidify and react chemically with one another. They are never rigidly inert structures.

Natural materials resist the movement of material bodies to differing degrees.

Natural space does not resist the movement of material bodies to any degree.

Natural space is translucent, but not heat-conducting or absorbing, light-absorbing, light-reflecting or a source of light.

Sub-atomic identities do not consistently behave in accordance with mechanical cause and effect.

Living organisms display sentience and depend for their sustainability on forming relationships with one another and their surroundings, from which they gather the sources of energy they need to thrive.

Human beings are emotional creatures.



Evolution is a product of co-creative fluid relationship, not selective preservation of favoured varieties and removal of others.

Mechanical causation is not primary causation.

Emotionality is an expression of natural energy flow.

Organisms are primarily needful, not selfish.

Opposition, enmity, competition and co-operation are human constructs based on definitive logic, not necessarily natural occurrences.

Love is a natural occurrence, not a human construct.

Wholes and parts, in the sense of completely definable entities, do not exist naturally.

Utter stillness is a quality of intangible space, not tangible structur.

Positivity (‘generosity’) cannot exist without negativity (‘receptivity’), and neither can ‘current.

Modes of Inquiry

Based solely on actual experience of natural phenomena.

Do not invent what is not known to exist for the sake of theoretical or practical convenience. Rigorously subject all truth claims, assumptions and hypotheses to two questions: (1) Is this consistent with actual experience? (2) Does this make consistent, non-paradoxical sense?

Include all traditional modes of scientific observation, measurement, experimentation and analysis, but do not objectively isolate observer from observation.

Instead combine intimate (first person) with distanced (third person) modes of perception, to enable relational/empathetic (second person) perception.

Intuitive, aesthetic, imaginative, empathetic, poetic modes of enquiry and expression are all valid, so long

Sources of Reference


Rayner, A.D.M (2017) The Origin of Life Patterns – In the natural inclusion of space in flux. SpringerBriefs in Psychology and Cultural Developmental Science (G. Marsico and J. Valsiner series editors). Springer.

Rayner, A.D.M. (2011) NaturesScope: Unlocking our natural empathy and creativity - an inspiring new way of relating to our natural origins and one another through natural inclusion. O Books.



Essays on Web

Patterns of Life – Stars & Stripes, Circles, Lines, Spirals, Ripples, Rivers and Crazy Paving in the Natural World

The (True) Nature of Time

Never Quite Knowing - Self as a Natural Centre of Circulation

Natural Companionship

Natural Flow-Form: A Mutual Inclusion of Strength and Weakness

Holding Openness

The Nature of Receptive Omnipresence

Bombshells - The Devastating Mistakes of Abstract Perception

From Abstract to Natural Perception – Through the ‘Space Barrier’ to a Refreshing New Understanding of Life and Love

Inclusional Sustainability

Estrangement and Reconciliation

Natural Co-Creation


Bio-Etheric Healing: Make Friends With Your Etheric Body. - Dragonfly Kingdom Library

Posted on April 10, 2021 at 7:10 AM Comments comments (0)

Bio-Etheric Healing is an innovative method of alternative healing which uses a set of Communication Skills based on thought processes to direct our Etheric Body, and through it, our full energy field (our Aura) to help in healing work. It is possible to have this communication directly with one's own energy field. Also, when working with a client, a Bio-Etheric Healing professional can use this method to mobilize the client's own energy field to help in his healing. The actual healing work is not limited to face-to-face physical proximity. Rather, Bio-Etheric Healing via thought process communication can be accomplished over great distances.

This communication, and the healing work itself, is possible because of the energy field which surrounds our bodies, and indeed surrounds everyone and everything on this planet. It is called the Auric Field, and our own individual envelope of this energy which surrounds our bodies is called our Aura. The first layer of our Aura, closest to our Physical Bodies, is the Etheric Layer, and it plays a major role in Bio-Etheric Healing.

In almost all cases, the actual healing itself begins at the Etheric Body level. It is primarily with the Etheric Body that we communicate with thought messages to provide it the directions for healing. It is in a sense the "supervisor" of the process. The Etheric Body then communicates with the other participants and enlists their help, as needed, to accomplish the healing. These other players include the Physical Body, the Brain, the other layers of the Aura, and the Chakra System. Each of these have special functions in the healing process, and the appropriate one must be called upon by the Etheric Body to aid in the process. The Chakra System is a major player because of its unique role as the distribution system for energy flow throughout the body.

However, even though the Etheric Body may know what is wrong and what needs healing, it won't act unless told to do so. The key to Bio-Etheric Healing is that we ourselves, or a healer, must give the Etheric Body directions as to what to do and it will do it.

When the Etheric Body is asked to heal something, it does the best it is able to do, with the information has. The more information provided to the Etheric Body, and the greater the accuracy of the information, the better it can accomplish its healing role

Effects of (-)-epicatechin on molecular modulators of skeletal muscle growth and differentiation. - Dragonfly Kingdom Library

Posted on April 8, 2021 at 8:00 AM Comments comments (0)

Effects of (−)-epicatechin on molecular modulators of skeletal muscle growth and differentiation

Gabriela Gutierrez-Salmean, Theodore P. Ciaraldi, [...], and Israel Ramirez-Sanchez


Additional article information



Sarcopenia is a notable and debilitating age-associated condition. Flavonoids are known for their healthy effects and limited toxicity. The flavanol (−)-epicatechin (Epi) enhances exercise capacity in mice and Epi-rich cocoa improves skeletal muscle structure in heart failure patients. (−)-Epicatechin may thus, hold promise as treatment for sarcopenia.


We examined changes in protein levels of molecular modulators of growth and differentiation in young vs. old, human and mouse skeletal muscle. We report the effects of Epi in mice and the results of an initial proof-of-concept trial in humans, where muscle strength and levels of modulators of muscle growth were measured. In mice, myostatin and senescence-associated β-galactosidase levels increase with aging, while those of follistatin and Myf5 decrease. (−)-Epicatechin decreases myostatin and β-galactosidase and increases levels of markers of muscle growth. In humans, myostatin and β-galactosidase increase with aging while follistatin, MyoD and myogenin decrease. Treatment for 7 days with (−)-epicatechin increases hand grip strength and the ratio of plasma follistatin/myostatin.


In conclusion, aging has deleterious effects on modulators of muscle growth/differentiation, the consumption of modest amounts of the flavanol (−)-epicatechin can partially reverse these changes. This flavanol warrants its comprehensive evaluation for the treatment of sarcopenia


Keywords: Epicatechin, sarcopenia, flavanoids........ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857584/ ;

Indexed for NIH by Dragonfly Kingdom Library

The Doctrine of Dependent Origination as Basis for a Paradigm of Human-Nature Relationship of Responsibility and Accountability. - Dragonfly Kingdom Library

Posted on April 6, 2021 at 10:25 AM Comments comments (0)

The Doctrine of Dependent Origination as Basis for a Paradigm of Human-Nature Relationship of Responsibility and Accountability

Journal of Graduate Studies Review of Mahachulalongkornrajavidyalaya University, Vol.11, No.1, January-April 2015, pp. 123-144

Posted: 26 Oct 2017
Anthony Le Duc
Lux Mundi National Major Seminary, Thailand

Date Written: March 15, 2015

The doctrine of paṭiccasamuppāda or Dependent Origination is one of the most important teachings of Buddhism and serves as a source of inspiration for reflections on all kinds of issues including social, political, and spiritual. In this paper, the doctrine of Dependent Origination is examined as a resource for conceiving of a relationship between human beings and nature as one characterized by responsibility. This is done by reflecting upon the abstract form of the teaching as a law of universal causality that contains an environmental import. The environmental significance of this teaching appears when we realize that human thoughts and actions can lead certain things to arise in nature that may be either positive or negative. Based on these reflections, a paradigm of human-nature relationship of responsibility is proposed. In addition, the Buddhist virtues of moderation and contentment are presented as essential ways to nourish such a relationship.

Indexed for SSRN by Dragonfly Kingdom Library 

One Element. We recognise but one element in Nature (whether spiritual or physical) outside which there can be no Nature since it is Nature itself... - Dragonfly Kingdom Library

Posted on April 6, 2021 at 7:40 AM Comments comments (0)

The Elements, in many philosophies and religious views, are said to be the simplest essential parts and principles of which everything consists. In ancient thought (such as the Greek, Hindu and Buddhist) there is reference to four elements (Earth, Water, Air, and Fire), sometimes including a fifth element or quintessence called Aether or Akasa (space). The Chinese had a somewhat different series of elements, namely Fire, Earth, Metal, Water and Wood, which were understood as different types of energy in a state of constant interaction and flux with one another, rather than the notion of different kinds of material. In the Theosophical literature there is mention to one ultimate element that differentiate in seven, although only four are completely manifested at this stage of evolution.



1 Elements in Theosophy

1.1 The One Element

1.2 Manifestation of the elements

2 In Hinduism

3 In Buddhism

3.1 The element or "dhatu"

4 In Greek philosophy

5 In Chinese philosophy

6 Notes

Elements in Theosophy

The Theosophical view maintains that there are seven fundamental elements in nature, which are differentiations of the one element. These seven elements do not manifest on all the planes simultaneously, but progressively as evolution goes on.


The One Element

In The Mahatma Letters, Master KH writes about one element, which is the homogeneous basis of all:


There is but one element and it is impossible to comprehend our system before a correct conception of it is firmly fixed in one's mind. You must therefore pardon me if I dwell on the subject longer than really seems necessary. But unless this great primary fact is firmly grasped the rest will appear unintelligible. This element then is the — to speak metaphysically — one sub-stratum or permanent cause of all manifestations in the phenomenal universe.[1]

This element is sometimes called Svābhāvat:


You will have first of all to view the eternal Essence, the Swabavat, not as a compound element you call spirit-matter, but as the one element for which the English has no name. It is both passive and active, pure Spirit Essence in its absoluteness, and repose, pure matter in its finite and conditioned state[2]

The one element penetrates the whole space and, in fact, is space itself:


We recognise but one element in Nature (whether spiritual or physical) outside which there can be no Nature since it is Nature itself, and which as the akasa pervades our solar system, every atom being part of itself pervades throughout space and is space in fact, which pulsates as in profound sleep during the pralayas, and [is] the universal Proteus, the ever active Nature during the manwantaras. . . . Consequently spirit and matter are one, being but a differentiation of states not essences.[3]

The great difficulty in grasping the idea in the above process lies in the liability to form more or less incomplete mental conceptions of the working of the one element, of its inevitable presence in every imponderable atom, and its subsequent ceaseless and almost illimitable multiplication of new centres of activity without affecting in the least its own original quantity.[4]

The one element not only fills space and is space, but interpenetrates every atom of cosmic matter.[5]

This one element is the origin of the different elements known by the ancients:


If the student bears in mind that there is but One Universal Element, which is infinite, unborn, and undying, and that all the rest — as in the world of phenomena — are but so many various differentiated aspects and transformations (correlations, they are now called) of that One, from Cosmical down to microcosmical effects, from super-human down to human and sub-human beings, the totality, in short, of objective existence — then the first and chief difficulty will disappear and Occult Cosmology may be mastered.[6]

Metaphysically and esoterically there is but One ELEMENT in nature, and at the root of it is the Deity; and the so-called seven elements, of which five have already manifested and asserted their existence, are the garment, the veil, of that deity; direct from the essence whereof comes MAN, whether physically, psychically, mentally or spiritually considered.[7]

The ancients speak of the five cognizable elements of ether, air, water, fire, earth, and of the one incognizable element (to the uninitiates) the 6th principle of the universe — call it Purush Sakti, while to speak of the seventh outside the sanctuary was punishable with death. But these five are but the differentiated aspects of the one.[8]

Manifestation of the elements

The process of cosmic manifestation proceeds gradually, manifesting six of these elements one after the other. Stanza VI.3 says:


Of the Seven (elements)—first one manifested, six concealed; two manifested—five concealed; three manifested—four concealed; four produced—three hidden; four and one tsan (fraction) revealed—two and one half concealed; six to be manifested—one laid aside.[9]

Mme. Blavatsky applies this sloka to the manifestation of the elements on the lowest plane, one at a time, with the succession of Rounds:


Although these Stanzas refer to the whole Universe after a Mahapralaya (universal destruction), yet this sentence, as any student of Occultism may see, refers also by analogy to the evolution and final formation of the primitive (though compound) Seven Elements on our Earth. Of these, four elements are now fully manifested, while the fifth—Ether—is only partially so, as we are hardly in the second half of the Fourth Round, and consequently the fifth Element will manifest fully only in the Fifth Round.[10]

Occult Science recognises Seven Cosmical Elements—four entirely physical, and the fifth (Ether) semi-material, as it will become visible in the air towards the end of our Fourth Round, to reign supreme over the others during the whole of the Fifth. The remaining two are as yet absolutely beyond the range of human perception. These latter will, however, appear as presentments during the 6th and 7th Races of this Round, and will become known in the 6th and 7th Rounds respectively. These seven elements with their numberless Sub-Elements far more numerous than those known to Science) are simply conditional modifications and aspects of the ONE and only Element.[11]

Four elements only are generally spoken of in later antiquity, five admitted only in philosophy. For the body of ether is not fully manifested yet, and its noumenon is still “the Omnipotent Father—Æther, the synthesis of the rest.”[12]

The succession of primary aspects of Nature with which the succession of Rounds is concerned, has to do, as already indicated, with the development of the “Elements” (in the Occult sense)—Fire, Air, Water, Earth. We are only in the fourth Round, and our catalogue so far stops short.[13]

The ordering of the elements mentioned by Mme. Blavatsky coincides with the degree of their spiritual quality. In a letter to Alfred Percy Sinnett, Mahatma K.H. wrote about:


. . . the principles of earth, water, air, fire and ether (akasa) following the order of their spirituality and beginning with the lowest.[14]

The elements can also be seen as the objective aspect of the seven Dhyani-Buddhas:


“These Brâhmanas (the Rishi Prajâpati?), the creators of the world, are born here (on earth) again and again. Whatever is produced from them is dissolved in due time in those very five great elements (the five, or rather seven, Dhyani Buddhas, also called “Elements” of Mankind), like billows in the ocean. These great elements are in every way beyond the elements that make up the world (the gross elements). And he who is released even from these five elements (the tanmâtras) goes to the highest goal.”[15]

In Hinduism

Hindus believe that all of creation, including the human body, is made up of these five essential elements (Mahābhūtas) and that upon death, the human body dissolves into these five elements of nature, thereby balancing the cycle of nature. These "five great elements" (panchamahābhūtas) are (in order of increasing subtlety):


1- Earth (pṛithvī or bhūmi)


2- Water (apa or jala)


3- Fire (tejas or agni)


4- Air or wind (vāyu)


5- Aether or space (akash).


The five great elements originate from the five tanmatra (subtle essences).


In Buddhism

The element or "dhatu"

The teaching about the existence of one single element, eternal and immutable, is not prevalent within Buddhism, which generally postulates Śūnyatā (emptiness) as the ultimate reality. However, as David Reigle has shown, the Jonangpa school of Tibetan Buddhism holds this teaching. He writes:


The key term in Maitreya's Ratna-gotra-vihhaga is dhātu, or element. It is described in the following important verse:

It is not born, does not die, is not afflicted, and does not grow old, because it is permanent (nitya/rtag-pa), stable (dhruva/brtan-pa), quiescent (siva/zhi-ba), and eternal (sasvata/g.yung-drung). Ratna-gotra-vibhaga or Uttara-tantra, by Maitreya, verse 80.

As noted earlier, this one thing, dhatu or element, may be called tathagata-garbha or Buddha-nature when obscured, and dharma-kaya or body of the law when unobscured.....

Indexed for Theosophy Wiki by Dragonfly Kingdom Library


Marco invited you to earn money hosting campers on Hipcamp. Earn $100+ from your first camper, guaranteed. - Marco's Fitness Travel at

Posted on April 4, 2021 at 8:15 AM Comments comments (0)

Marco invited you to earn money hosting campers on Hipcamp

Earn $100+ from your first camper, guaranteed.


Antiviral oxysterols are present in human milk at diverse stages of lactation. -- Dragonfly Kingdom Library

Posted on March 31, 2021 at 7:30 AM Comments comments (0)

J Steroid Biochem Mol Biol

. 2019 Oct;193:105424. doi: 10.1016/j.jsbmb.2019.105424. Epub 2019 Jul 11.

Antiviral oxysterols are present in human milk at diverse stages of lactation

Andrea Civra 1, Valerio Leoni 2, Claudio Caccia 3, Stefano Sottemano 4, Paola Tonetto 4, Alessandra Coscia 4, Chiara Peila 4, Guido E Moro 5, Pietro Gaglioti 6, Enrico Bertino 4, Giuseppe Poli 7, David Lembo 8

PMID: 31302219

DOI: 10.1016/j.jsbmb.2019.105424


Oxysterols are cholesterol oxidation derivatives. Those containing an additional hydroxyl group on the side chain of the cholesterol molecule result from a physiological enzymatic synthesis and include the majority of oxysterols present in the circulation. Among these, 25-hydroxycholesterol (25OHC) and 27-hydroxycholesterol (27OHC) are characterized by a broad antiviral activity and are now considered involved in the innate immune response against viruses. Despite the emerging role of these sterols in the innate antiviral defences, no data are available on their presence in human breast milk (BM) to date. In this study, we investigated the content of oxysterols of enzymatic synthesis in BM of twelve donor mothers at different stages of lactation (i.e. in colostrum, transitional milk, and mature milk) by gas chromatography-mass spectrometry analysis. The side-chain oxysterols 25OHC, 27OHC, and 24S-hydroxycholesterol (24SOHC) were actually present in BM in all stages of lactation, but the concentration of 27OHC showed a remarkable peak in colostrum. Antiviral assays revealed that all the colostrum samples contained 27OHC concentrations that were active in vitro against two relevant pediatric viral pathogens: the human rotavirus and the human rhinovirus. Overall, this study discloses new antiviral components of BM and suggests a passive transfer of these protective factors to the infant via breastfeeding, especially in the first few days of lactation.


Keywords: Antiviral; Colostrum; Maternal milk; Oxysterols; Rhinovirus; Rotavirus 

....... Indexed for NIH Pubmed by Dragonfly Kingdom Library


Evaluation of current studies suggests that EMF may represent a serious source of concern and may be hazardous to living organisms. EMF triggers the increase of free radical in the cell by the Fenton re- action (Lai and Singh, 2004). -- Dragonfly Kingdom

Posted on March 29, 2021 at 1:55 PM Comments comments (0)

Genotoxic and carcinogenic effects of non-ionizing electromagnetic fields

Adem Kocaman⁎
, Gamze Altun, Arife Ahsen Kaplan, Ömür Gülsüm Deniz, Kıymet Kübra Yurt,
Süleyman Kaplan

Department of Histology and Embryology, Medical Faculty, Ondokuz Mayıs University, Samsun, Turkey

Electromagnetic field


New technologies in electronics and communications are continually emerging. An increasing use of these
electronic devices such as mobile phone, computer, wireless fidelity connectors or cellular towers is raising
questions concerning whether they have an adverse effect on the body. Exposure to electromagnetic fields (EMF)
is frequently suggested to have adverse health effects on humans and other organisms. This idea has been
reported in many studies. In contrast, the therapeutic effects of EMF on different organs have also been reported.
Research findings are inconsistent. This has given rise to very profound discrepancies. The duration and fre-
quency of mobile phone calls and the association observed with various health effects has raised serious concerns
due to the frequency with which these devices are used and the way they are held close to the head. The present
review assesses the results of in vitro, in vivo, experimental, and epidemiological studies. The purpose of the study
is to assess data concerning the carcinogenic and genotoxic effects of non-ionizing EMF. The major genotoxic and
carcinogenic effects of EMF, divided into subsections as low frequency effects and radiofrequency effects, were
reviewed. The inconsistent results between similar studies and the same research groups have made it very
difficult to make any comprehensive interpretation. However, evaluation of current studies suggests that EMF
may represent a serious source of concern and may be hazardous to living organisms......... https://ecfsapi.fcc.gov/file/1091314126731/Genotoxic and carcinogenic effects of non-ionizing electromagnetic fields.pdf

Indexed for FCC.gov , Science Direct , Elsevier

Deconstructing Medicine: The Alternative Cellular Energy Pathway. -- Dragonfly Kingdom Library

Posted on March 29, 2021 at 6:55 AM Comments comments (0)



The pharmaceutical model for treating chronic illnesses has largely dominated the practice of medicine since the Flexner report of 1910. It essentially entails biochemical based endeavors to correct detectable or discerned metabolic imbalances in diseased cells. These manipulations almost invariably alter the metabolism of normal cells leading to predictable adverse side effects. Enhancing cellular energy can potentially help overcome cellular impairments in diseased cells without necessarily affecting normal cells. The identification of the alternative cellular energy (ACE) pathway, expressed as a dynamic (kinetic) quality of biological fluids, is providing a useful new paradigm for universally applicable therapeutic endeavors. This article reviews the current understanding of the fluid activation process. It appears to be mediated by a repulsive environmental force termed KELEA (kinetic energy limiting electrostatic attraction), which reduces the strength of intermolecular hydrogen bonding. Various means of imparting KELEA to drinking water are discussed. The article is intended to encourage widespread clinical evaluation of KELEA activated “ACE Water” as a waterceuticalÔ in the prevention and therapy of many clinical illnesses.


Keywords: KELEA alternative cellular energy ACE Pathway ACE water waterceuticalTM enerceuticalTM stealth adapted viruses energy medicine chronic illnesses 

Martin, W. J. (2015). Deconstructing Medicine: The Alternative Cellular Energy Pathway. Journal of Advances in Medicine and Medical Research, 11(8), 1-6. https://doi.org/10.9734/BJMMR/2016/21484

Coronavirus Sars-Cov inactivated by ultraviolet light (UV) at 254 nm, heat treatment of 65 °C or greater, alkaline (pH > 12) or acidic (pH < 3) conditions. -- Dragonfly Kingdom Library

Posted on March 28, 2021 at 10:00 AM Comments comments (0)

Inactivation of the coronavirus that induces severe acute respiratory syndrome, SARS-CoV

Miriam E.R. Darnell, Kanta Subbarao, [...], and Deborah R. Taylor

Additional article information

Severe acute respiratory syndrome (SARS) is a life-threatening disease caused by a novel coronavirus termed SARS-CoV. Due to the severity of this disease, the World Health Organization (WHO) recommends that manipulation of active viral cultures of SARS-CoV be performed in containment laboratories at biosafety level 3 (BSL3). The virus was inactivated by ultraviolet light (UV) at 254 nm, heat treatment of 65 °C or greater, alkaline (pH > 12) or acidic (pH < 3) conditions, formalin and glutaraldehyde treatments. We describe the kinetics of these efficient viral inactivation methods, which will allow research with SARS-CoV containing materials, that are rendered non-infectious, to be conducted at reduced safety levels.

Keywords: SARS, Coronavirus, Virus inactivation, Tissue culture
1. Introduction
In late 2002, an outbreak of unusual life-threatening respiratory disease of unknown etiology began in Guangdong Province, China. This disease was designated severe acute respiratory syndrome (SARS) and was later determined by Drosten et al. (2003), Ksiazek et al. (2003), and Rota et al. (2003), to be caused by a novel coronavirus, termed SARS-CoV. Since the identification of coronavirus as the infectious agent for SARS, numerous laboratories have begun research on this virus. According to the WHO, 8098 people were diagnosed with SARS and 774 people died of this disease during the initial outbreak of 2003. Due to the severity of SARS disease and the contagious nature of the causal agent, the WHO website (http://www.who.int/csr/sars/biosafety2003_12_18/en/) has provided guidelines for working safely with this coronavirus. The WHO recommends biosafety level 3 (BSL3) as the appropriate containment level for working with live SARS-CoV, and there is a concern that another SARS outbreak could occur following an accidental exposure in a laboratory. Since the end of the SARS epidemic in July 2003, there have been three known cases of SARS in laboratory researchers due to accidental exposure to the virus (Normile, 2004). Successful inactivation of the virus allows the transfer of material from a BSL3 to a BSL2 environment and may reduce the risk of accidental infections through unsafe laboratory practices. Inactivated cell-culture derived viral stocks may also be useful for the development of vaccines and the study of their safety and immunogenicity. We examined the efficiency of several methods of viral inactivation, including methods that may inhibit viral replication or entry.......... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112912/

Indexed for NIH by Dragonfly Kingdom Library

These results provide a basis for the use of traditional medicinal plants as alternative lines of treatment for COVID-19 infection. -- Dragonfly Kingdom Library

Posted on March 26, 2021 at 8:30 AM Comments comments (0)

In silico studies reveal potential antiviral activity of

phytochemicals from medicinal plants for the

treatment of COVID-19 infection


Mansi Pandit

Bioinformatics center, Sri Venkateswara College, University of Delhi

N. Latha

Bioinformatics center, Sri Venkateswara College, University of Delhi

lata@bic-svc.ac.inCorresponding Author




Structural Biology Bioinformatics


SARS-CoV-2, Drug Targets, Phytochemicals, Medicinal Plants, Docking, Binding



The spread of COVID-19 across continents has led to a global health emergency. COVID-19 disease

caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected nearly all

the continents with around 1.52 million confirmed cases worldwide. Currently only a few regimes have

been suggested to fight the infection and no specific antiviral agent or vaccine is available.

Repurposing of the existing drugs or use of natural products are the fastest options available for the

treatment. The present study is aimed at employing computational approaches to screen

phytochemicals from the medicinal plants targeting the proteins of SARS-CoV2 for identification of

antiviral therapeutics. The study focuses on three target proteins important in the life cycle of SARS-

CoV-2 namely Spike (S) glycoprotein, main protease (Mpro) and RNA-dependent RNA-polymerase

(RdRp). Molecular docking was performed to screen phytochemicals in medicinal plants to determine

their feasibility as potential inhibitors of these target viral proteins. Of the 30 plant phytochemicals

screened, Silybin, an active constituent found in Silybum marianum exhibited higher binding affinity

with targets in SARS-CoV-2 in comparison to currently used repurposed drugs against SARS-CoV-

2. Withaferin A from Withania somnifera also showed significant binding to the targets proteins. In

addition, phytochemicals from Tinospora cordiofolia and Aloe barbadensis displayed good binding

energetics with the target proteins in SARS-CoV-2. These results provide a basis for the use of

traditional medicinal plants as alternative lines of treatment for COVID-19 infection.

Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture. -- Dragonfly Kingdom Library

Posted on March 26, 2021 at 8:10 AM Comments comments (0)

Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture

Aartjan J. W. te Velthuis, Sjoerd H. E. van den Worm, Amy C. Sims, Ralph S. Baric, Eric J. Snijder, Martijn J. van Hemert

1. Lazarczyk M, Favre M (2008) Role of Zn2+ ions in host-virus interactions. J Virol 82: 11486–11494.
View Article
Google Scholar
2. Frederickson CJ, Koh JY, Bush AI (2005) Neurobiology of zinc in health and disease. Nat Rev Neurosci 6: 449–462.
View Article
Google Scholar
3. Alirezaei M, Nairn AC, Glowinski J, Premont J, Marin P (1999) Zinc inhibits protein synthesis in neurons: potential rol of phosphorylation of translation initiation factor-2a. J Biol Chem 274: 32433–32438.
View Article
Google Scholar
4. Uchide N, Ohyama K, Bessho T, Yuan B, Yamakawa T (2002) Effect of antioxidants on apoptosis induced by influenza virus infection: inhibition of viral gene replication and transcription with pyrrolidine dithiocarbamate. Antiviral Res 56: 207–217.
View Article
Google Scholar
5. Suara RO, Crowe JEJ (2004) Effect of zinc salts on respiratory syncytial virus replication. Antimicrob Agents Chemother 48: 783–790.
View Article
Google Scholar
6. Gaudernak E, Seipelt J, Triendl A, Grassauer A, Kuechler E (2002) Antiviral Effects of Pyrrolidine Dithiocarbamate on Human Rhinoviruses. J Virol 76: 6004–6015.
View Article
Google Scholar
7. Si X, McManus BM, Zhang J, Yuan J, Cheung C, et al. (2005) Pyrrolidine Dithiocarbamate Reduces Coxsackievirus B3 Replication through Inhibition of the Ubiquitin-Proteasome Pathway. J Virol 79: 8014–8023.
View Article
Google Scholar
8. Korant BD, Kauer JC, Butterworth BE (1974) Zinc ions inhibit replication of rhinoviruses. Nature 248: 588–590.
View Article
Google Scholar
9. Polatnick J, Bachrach HL (1978) Effect of zinc and other chemical agents on foot-and-mouth-disease virus replication. Antimicrob Agents Chemother 13: 731–734.
View Article
Google Scholar
10. Lanke K, Krenn BM, Melchers WJG, Seipelt J, van Kuppeveld FJM (2007) PDTC inhibits picornavirus polyprotein processing and RNA replication by transporting zinc ions into cells. J Gen Virol 88: 1206–1217.
View Article
Google Scholar
11. Krenn BM, Gaudernak E, Holzer B, Lanke K, Van Kuppeveld FJM, et al. (2009) Antiviral Activity of the Zinc Ionophores Pyrithione and Hinokitiol against Picornavirus Infections. J Virol 83: 58–64.
View Article
Google Scholar
12. Zalewski PD, Forbes IJ, Betts WH (1993) Correlation of apoptosis with change in intracellular labile Zn(II) using Zinquin [(2-methyl-8-p-toluenesulphonamide-6-quinolyloxy)acetic acid], a new specific fluorescent probe for Zn(II). Biochem J 296: 403–408.
View Article
Google Scholar
13. Baum EZ, Bebernitz GA, Palant O, Mueller T, Plotch SJ (1991) Purification, properties, and mutagenesis of poliovirus 3C protease. Virology 165: 140–150.
View Article
Google Scholar
14. Cordingley MG, Register RB, Callahan PL, Garsky VM, Colonno RJ (1989) Cleavage of small peptides in vitro by human rhinovirus 14 3C protease expressed in Escherichia coli. J Virol 63: 5037–5045.
View Article
Google Scholar
15. Ferrari E, Wright-Minogue J, Fang JW, Baroudy BM, Lau JY, et al. (1999) Characterization of soluble hepatitis C virus RNA-dependent RNA polymerase expressed in Escherichia coli. J Virol 73: 1649–1654.
View Article
Google Scholar
16. Hung M, Gibbs CS, Tsiang M (2002) Biochemical characterization of rhinovirus RNA-dependent RNA polymerase. Antiviral Res 56: 99–114.
View Article
Google Scholar
17. Perlman S, Netland J (2009) Coronaviruses post-SARS: update on replication and pathogenesis. Nat Rev Micro 7: 439–450.
View Article
Google Scholar
18. Gorbalenya AE, Enjuanes L, Ziebuhr J, Snijder EJ (2006) Nidovirales: evolving the largest RNA virus genome. Virus Res 117: 17–37.
View Article
Google Scholar
19. Snijder EJ, Bredenbeek PJ, Dobbe JC, Thiel V, Ziebuhr J, et al. (2003) Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage. J Mol Biol 331: 991–1004.
View Article
Google Scholar
20. Pasternak AO, Spaan WJ, Snijder EJ (2006) Nidovirus transcription: how to make sense…? J Gen Virol 80: 1403–1421.
View Article
Google Scholar
21. Sawicki SG, Sawicki DL, Siddell SG (2007) A Contemporary View of Coronavirus Transcription. J Virol 81: 20–29.
View Article
Google Scholar
22. Butterworth BE, Korant BD (1974) Characterization of the large picornaviral polypeptides produced in the presence of zinc ion. J Virol 14: 282–291.
View Article
Google Scholar
23. Denison MR, Perlman S (1986) Translation and processing of mouse hepatitis virus virion RNA in a cell-free system. J Virol 60: 12–18.
View Article
Google Scholar
24. Denison MR, Zoltick PW, Hughes SA, Giangreco B, Olson AL, et al. (1992) Intracellular processing of the N-terminal ORF 1a proteins of the coronavirus MHV-A59 requires multiple proteolytic events. Virology 189: 274–284.
View Article
Google Scholar
25. van Hemert MJ, de Wilde AH, Gorbalenya AE, Snijder EJ (2008) The in Vitro RNA Synthesizing Activity of the Isolated Arterivirus Replication/Transcription Complex Is Dependent on a Host Factor. J Biol Chem 283: 16525–16536.
View Article
Google Scholar
26. van Hemert MJ, van den Worm SHE, Knoops K, Mommaas AM, Gorbalenya AE, et al. (2008) SARS-Coronavirus Replication/Transcription Complexes Are Membrane-Protected and Need a Host Factor for Activity In Vitro. PLoS Pathog 4: e1000054.
View Article
Google Scholar
27. te Velthuis AJ, Arnold JJ, Cameron CE, van den Worm SH, Snijder EJ (2009) The RNA polymerase activity of SARS-coronavirus nsp12 is primer dependent. Nucleic Acids Res 38: 203–214.
View Article
Google Scholar
28. Beerens N, Selisko B, Ricagno S, Imbert I, van der Zanden L, et al. (2007) De Novo Initiation of RNA Synthesis by the Arterivirus RNA-Dependent RNA Polymerase. J Virol 81: 8384–8395.
View Article
Google Scholar
29. van den Born E, Posthuma CC, Knoops K, Snijder EJ (2007) An infectious recombinant equine arteritis virus expressing green fluorescent protein from its replicase gene. J Gen Virol 88: 1196–1205.
View Article
Google Scholar
30. Sims AC, Burkett SE, Yount B, Pickles RJ (2008) SARS-CoV replication and pathogenesis in an in vitro model of the human conducting airway epithelium. Virus Res 133: 33–44.
View Article
Google Scholar
31. Xu X, Liu Y, Weiss S, Arnold E, Sarafianos SG, et al. (2003) Molecular model of SARS coronavirus polymerase: implications for biochemical functions and drug design. Nucleic Acids Res 31: 7117–7130.
View Article
Google Scholar
32. Zhai Y, Sun F, Li X, Pang H, Xu X, et al. (2005) Insights into SARS-CoV transcription and replication from the structure of the nsp7-nsp8 hexadecamer. Nat Struct Mol Biol 12: 980–986.
View Article
Google Scholar
33. Stockman LJ, Bellamy R, Garner P (2006) SARS: Systematic Review of Treatment Effects. PLoS Med 3: e343.
View Article
Google Scholar
34. Thompson A, Patel K, Tillman H, McHutchison JG (2009) Directly acting antivirals for the treatment of patients with hepatitis C infection: A clinical development update addressing key future challenges. J Hepatol 50: 184–194.
View Article
Google Scholar
35. De Clercq E (2004) Antivirals and antiviral strategies. Nat Rev Microbiol 2: 704–720.
View Article
Google Scholar
36. Thompson AJV, McHutchison JG (2009) Antiviral resistance and specifically targeted therapy for HCV (STAT-C). J Viral Hepat 16: 377–387.
View Article
Google Scholar
37. Yang W, Lee JY, Nowotny M (2006) Making and Breaking Nucleic Acids: Two-Mg2+-Ion Catalysis and Substrate Specificity. Mol Cell 22: 5–13.
View Article
Google Scholar
38. Castro C, Smidansky E, Maksimchuk KR, Arnold JJ, Korneeva VS, et al. (2007) Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases. Proc Natl Acad Sci USA 104: 4267–4272.
View Article
Google Scholar
39. Arnold JJ, Ghosh SK, Cameron CE (1999) Poliovirus RNA-dependent RNA Polymerase (3Dpol). Divalent cation modulation of primer, template and nucleotide selection. J Biol Chem 274: 37060–37069.
View Article
Google Scholar
40. Iuchi S (2001) Three classes of C2H2 zinc finger proteins. Cell Mol Life Sci 58: 625–635.
View Article
Google Scholar
41. Gomis-Ruth XF (2009) Catalytic domain architecture of metzincin metalloproteases. J Biol Chem 284: 15353–15357.
View Article
Google Scholar
42. Yap TL, Xu T, Chen Y-L, Malet H, Egloff M-P, et al. (2007) Crystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom Resolution. J Virol 81: 4753–4765.
View Article
Google Scholar
43. Winek CL, Buehler EV (1966) Intravenous toxicity of zinc pyridinethione and several zinc salts. Toxicol Appl Pharmacol 9: 296–273.
View Article
Google Scholar
44. Snyder DR, de Jesus CP, Towfighi J, Jacoby RO, Wedig JH (1979) Neurological, microscopic and enzyme-histochemical assessment of zinc pyrithione toxicity. Food Cosmet Toxicol 17: 651–660.
View Article
Google Scholar
45. Magda D, Lecane P, Wang Z, Hu W, Thiemann P, et al. (2008) Synthesis and anticancer properties of water-soluble zinc ionophores. Cancer Res 68: 5318–5325.
View Article
Google Scholar
46. Snijder EJ, van der Meer Y, Zevenhoven-Dobbe J, Onderwater JJM, van der Meulen J, et al. (2006) Ultrastructure and Origin of Membrane Vesicles Associated with the Severe Acute Respiratory Syndrome Coronavirus Replication Complex. J Virol 80: 5927–5940.
View Article
Google Scholar
47. Studier F (2005) Protein production by auto-induction in high density shaking cultures. Protein Expr Purif 41: 207–234.
View Article
Google Scholar
Increasing the intracellular Zn2+ concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the replication of a variety of RNA viruses, including poliovirus and influenza virus. For some viruses this effect has been attributed to interference with viral polyprotein processing. In this study we demonstrate that the combination of Zn2+ and PT at low concentrations (2 µM Zn2+ and 2 µM PT) inhibits the replication of SARS-coronavirus (SARS-CoV) and equine arteritis virus (EAV) in cell culture. The RNA synthesis of these two distantly related nidoviruses is catalyzed by an RNA-dependent RNA polymerase (RdRp), which is the core enzyme of their multiprotein replication and transcription complex (RTC). Using an activity assay for RTCs isolated from cells infected with SARS-CoV or EAV—thus eliminating the need for PT to transport Zn2+ across the plasma membrane—we show that Zn2+ efficiently inhibits the RNA-synthesizing activity of the RTCs of both viruses. Enzymatic studies using recombinant RdRps (SARS-CoV nsp12 and EAV nsp9) purified from E. coli subsequently revealed that Zn2+ directly inhibited the in vitro activity of both nidovirus polymerases. More specifically, Zn2+ was found to block the initiation step of EAV RNA synthesis, whereas in the case of the SARS-CoV RdRp elongation was inhibited and template binding reduced. By chelating Zn2+ with MgEDTA, the inhibitory effect of the divalent cation could be reversed, which provides a novel experimental tool for in vitro studies of the molecular details of nidovirus replication and transcription.

Author Summary
Positive-stranded RNA (+RNA) viruses include many important pathogens. They have evolved a variety of replication strategies, but are unified in the fact that an RNA-dependent RNA polymerase (RdRp) functions as the core enzyme of their RNA-synthesizing machinery. The RdRp is commonly embedded in a membrane-associated replication complex that is assembled from viral RNA, and viral and host proteins. Given their crucial function in the viral replicative cycle, RdRps are key targets for antiviral research. Increased intracellular Zn2+ concentrations are known to efficiently impair replication of a number of RNA viruses, e.g. by interfering with correct proteolytic processing of viral polyproteins. Here, we not only show that corona- and arterivirus replication can be inhibited by increased Zn2+ levels, but also use both isolated replication complexes and purified recombinant RdRps to demonstrate that this effect may be based on direct inhibition of nidovirus RdRps. The combination of protocols described here will be valuable for future studies into the function of nidoviral enzyme complexes.

Citation: te Velthuis AJW, van den Worm SHE, Sims AC, Baric RS, Snijder EJ, van Hemert MJ (2010) Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture. PLoS Pathog 6(11): e1001176. https://doi.org/10.1371/journal.ppat.1001176

Indexed for PLOS ONE by Dragonfly Kingdom Library

Electric cars aren't really green. -- Dragonfly Kingdom Library

Posted on March 26, 2021 at 7:45 AM Comments comments (0)

Electric cars aren’t really green

The electric car has a secret—it isn’t actually green.


When people say an electric car is green, they are usually comparing it to a regular, internal combustion engine car, and most people are often very quick to conclude that electric cars are environmentally friendly. While that might be true in terms of their absence of exhaust emissions, many people are unaware of the environmental damage that happens as a result of manufacturing.


For instance, electric vehicles are charged by electricity that comes from burning fossil fuels or coal on an industrial scale and therefore cannot be labeled as clean or green. Similarly, manufacturing electric cars in general also burns fossil fuels.


The Toyota Prius is a well-known car globally. It is the world’s first mass-produced hybrid car. We all know it, automatically through advertising, as an environment friendly car. However, very few people know that Toyota acknowledges that Prius production is more carbon dioxide heavy than that of gas-engine cars, according to The New York Times.


Nearly all electric cars are powered by a lithium-ion battery, and cars that are completely electric have no exhaust systems. They function completely on batteries that have a different composition of lithium and other chemicals. Teslas are a popular example of such cars. Many people might be unaware that the heart of a Tesla—its batteries—come from Japan. The electronics giant Panasonic supplies battery cells for popular Tesla cars like the Model S, Model X and Model 3, sending about 3 million battery cells daily.


That requires a lot of lithium, and that isn’t a good thing, as analyst Christina Valimaki of online technology journal Elsevier, said to Wired, “One of the biggest environmental problems caused by our endless hunger for the latest and smartest devices is a growing mineral crisis, particularly those needed to make our batteries.” The demand for lithium is increasing exponentially, and it doubled in price between 2016 and 2018.


Lithium is found in the brine of salt flats. To obtain it, the flats are drilled to pump the brine to the surface. This allows lithium carbonate to be extracted via a chemical process, which isn’t exactly eco-friendly, and the damages it does are not always highlighted and are rarely included in any electric cars’ brochure.


South America is famous for these salt flats. Popularly known as “Lithium Triangle,” the area entails parts of Argentina, Bolivia and Chile and holds more than half the world’s supply of the metal. The extraction process is cheap, but it involves a lot of water—approximately 500,000 gallons for each tonne of lithium.


Local farmers of Salar de Atacama in Chile, for example, who grow quinoa and herd llamas, are already forced to travel for water. To add to this already existing water shortage, mining lithium consumes about 65% of the region’s water.


While water supplies are exhausted in some countries, the water gets contaminated in other places. In Tibet, for example, during the mining process, toxic hydrochloric acid—a chemical among many others that are used in the extraction process—leaked into the local water supply.


In Australia and North America, lithium mining also requires a lot of chemicals like hydrochloric acid, which ends up tampering any local nearby water source. The problem this creates is it compromises any wildlife in the water too. Research in Nevada on chemicals leaking into a local water source found that fish in a stream as far as 150 miles from the mining place are heavily affected.


Lithium extraction processes have unique devastating consequences depending on which country they are being extracted from. Regardless, they all cause air contamination and harm the soil, in some places, leaving the changes irreversible and the lands useless. There is no scope of labeling the extraction of Lithium as green. Chilean biologist Cristina Dorador told Bloomberg, “We’re fooling ourselves if we call this sustainable and green mining.”


Manufacturers should focus more on transparency of their batteries and not always prioritize profits. Other chemical combination may not be as energy dense as the lithium, cobalt and nickel cocktail, but that does not mean they should not be focused on. In addition, with an abundance of electronics existing, researches like the Faraday Challenge—a government-funded research at the University of Birmingham that focuses on lithium recycling—should be multiplied.


Regardless, in crude reality, manufacturers that make electric cars care about revenue. It is of little interest to them what impact their production has on the environment as long as cars are sold. Yet another example is Tesla’s recent decision to start production in China. Their brochures and advertisements will never highlight how many farmlands were driven to drought, or how they have switched to battery manufacturers that offer lithium batteries at a cheaper price, but at a great environmental cost.

Indexed for PSU Vanguard by Dragonfly Kingdom Library


The term KELEA (kinetic energy limiting electrostatic attraction) is proposed for a natural energy that increases the volatility of fluids, seemingly through the loosening of intermolecular hydrogen bonding. -- Dragonfly Kingdom Library

Posted on March 26, 2021 at 7:40 AM Comments comments (0)

Open Journal of Biophysics

Vol.05 No.03(2015), Article ID:58077,10 pages

10.4236/ojbiphy.2015.53006KELEA: A Natural Energy That Seemingly Reduces Intermolecular Hydrogen Bonding in Water and Other LiquidsW. John Martin

Institute of Progressive Medicine, South Pasadena, CA, USAEmail: wjohnmartin@ccid.orgCopyright © 2015 by author and Scientific Research Publishing Inc.This work is licensed under the Creative Commons Attribution International License (CC BY).http://creativecommons.org/licenses/by/4.0/Received 8 June 2015; accepted 14 July 2015; published 17 July 2015


The alternative cellular energy (ACE) pathway was initially identified as a non-immunological defense mechanism against virus infections. It is particularly relevant to the suppression of stealth adapted viruses, which are not normally recognized by the cellular immune system. Many of the methods able to enhance the ACE pathway are consistent with the transfer of a natural energy to the body’s fluids. Additional support for this premise is provided in this paper. The vapor pressure and rate of evaporation of activated water, ethanol and gasoline increase to beyond atmospheric pressure over time. The term KELEA (kinetic energy limiting electrostatic attraction) is proposed for a natural energy that increases the volatility of fluids, seemingly through the loosening of intermolecular hydrogen bonding. KELEA activated fluids have many potential health, agricultural and industrial applications, as well as providing the opportunity for fundamental research..........

Indexed for SCIRP by Dragonfly Kingdom Library


A Potential Non-Invasive Therapy to Treat COVID-19, As Yet Unrecognized in the Medical Literature. -- Dragonfly Kingdom Library

Posted on March 26, 2021 at 6:35 AM Comments comments (0)

1. Mitchell BW, King DJ (1994) Effect of negative air ionization
on airborne transmission of Newcastle disease virus. Avian
Dis 38: 725-732.
2. Susuki T, Kobayashi N (2004) Plasmacluster ions inacti-
vate an airborne coronavirus: A world first verification re-
search conducted jointly with the Kitasato Institute. Sharp
3. Scherlag BJ, Scherlag RA, Po SS (2020) Apparatus for
generating negative air ions: Inactivation of coronaviruses.
Lett Health and Biol Sci 5: 1-3.
4. Liu L, Wang P, Nair MS, Yu J, Rapp M, et al. (2020) Po-
tent neutralizing antibodies directed to multiple epitopes on
SARS-CoV-2 spike. Nature.
5. Duan HJ, Gao f, Oguchi K, Nagata T (1994) Light and elec-
tron microscopic radioautographic study on the incorpora-
tion of 3H-thymidine into the lung by means of a new nebu-
lizer. Arzneimittelforschung 44: 880-883.
6. Business Insider (2020) Used in large-scale ventilation sys-
tems worldwide, bipolar ionization could be a secret weap-
on in the war against COVID-19.
7. OU to Install specialized microbe-fighting devices in resi-
dence hall rooms, University of Oklahoma, June 12, 2020.

KELEA Activation of Water and Other Fluids for Health, Agriculture and Industry. -- Dragonfly Kingdom Library

Posted on March 26, 2021 at 5:25 AM Comments comments (0)

KELEA Activation of Water and Other Fluids for Health, Agriculture and Industry

W. John Martin*

Abstract: Water is a critical component in the functioning of the earth and of all living creatures. An important insight into the variable physical and biological properties of water has been provided by studies consistent with an external force termed KELEA (kinetic energy limiting electrostatic attraction) that weakens the intermolecular bonding of water molecules. Simple methods are described in this paper for producing and testing KELEA activated water. A summary is also provided of many major applications of KELEA activated water in health, agriculture and industry. While several of the proposed applications require more rigorous scientific documentation and further optimization, collectively they present the compelling opportunity for KELEA activated water to immediately transform medical, agricultural and industrial practices. A coordinated endeavor is proposed to better understand the science of KELEA and to develop simplified protocols for utilizing KELEA activated water and other fluids in the presently described and likely numerous additional applications. This ambitious undertaking envisions the cooperation among a range of specialized philanthropic organizations, working within different countries and with the strong support of national governments.

Keywords: KELEA, Water, Philanthropy, Insufficiency of Cellular Energy, Alternative Cellular Energy, ACE WaterTM, Dipolar Compounds, EnerceuticalTM, WaterceuticalTM, Homeopathy, GasolineTM

Cite this paper: Martin, W. (2015) KELEA Activation of Water and Other Fluids for Health, Agriculture and Industry. Journal of Water Resource and Protection, 7, 1331-1344. doi: 10.4236/jwarp.2015.716108.


[1] Martin, W.J. (2015) KELEA: A Natural Energy That Seemingly Reduces Intermolecular Hydrogen Bonding in Water and Other Liquids. Open Journal of Biophysics, 5, 69-79.




[2] Martin, W.J. (2015) Improved Efficiency of Heat Exchange Using KELEA Activated Water. Open Journal of Energy Efficiency, 4, 36-43.



[3] Martin, W.J. (2015) Therapeutic Potential of KELEA Activated Water. International Journal of Complementary & Alternative Medicine, 1, Article ID: 00001.



[4] Fischer, P. (2012) What Is Homeopathy? An Introduction. Frontiers in Bioscience (Elite Edition), 4, 1669-1682.




[5] Martin, W.J. (2014) Stealth Adapted Viruses; Alternative Cellular Energy (ACE) & KELEA Activated Water. AuthorHouse In., Bloomington, 321.



[6] Brown, Y.




[7] Cayce, E.




[8] Silver, N. (2011) The Rife Handbook of Frequency Therapy and Holistic Health. Desert Gate Productions Az., Phoenix, 742.



[9] Lakhovsky, G. (1996) The Secret of Life. Cosmic Rays and Radiations of Living Beings. Translated by Clement, M., Health Research, Pomeroy, 213.



[10] Martin, W.J. (2015) Interacting Light Paths Attract KELEA (Kinetic Energy Limiting Electrostatic Attraction) and Can Lead to the Activation of Water. Open Journal of Biophysics, 5, 115-121.




[11] Martin, W.J. (2015) Interactive Electric Fields Attract KELEA (Kinetic Energy Limiting Electrostatic Attraction) and Can Lead to the Activation of Water. International Journal of Complementary & Alternative Medicine, 1, Article ID: 00034.



[12] Reich, W. (1948) The Cancer Biopathy. The Discovery of the Orgone. Vol. 2, Translated by White, A., Higgins, M. and Raphael, C.M., Farrar, Straus and Giroux, New York, 433.



[13] Roerich, V.




[14] Mohorn, W.




[15] Pleasanton, A. (1877) The Influence of the Blue Ray of the Sunlight and of the Blue Color of the Sky. Remsen & Haffelfinger, Claxton, 185.



[16] Martin, W.J. (2015) Is the Brain an Activator of the Alternative Cellular Energy (ACE) Pathway? International Journal of Complementary & Alternative Medicine, 1, Article ID: 00002.



[17] Martin, W.J. (2014) Alternative Cellular Energy (ACE) Activation as Natural Therapy for Autism. In: Stealth Adapted Viruses; Alternative Cellular Energy (ACE) & KELEA Activated Water. AuthorHouse In., Bloomington, 87-102.



[18] Polack, G.H. (2013) The Fourth Phase of Water: Beyond Solid Liquid and Vapor. Ebner and Sons, Seattle, 357.



[19] DeMeo, J. (2014) Spectrographic Signatures in Water Induced by Radiant Fields from Enclosures of Various Materials. Presented at Conference on the Physics, Chemistry and Biology of Water, Bulgaria.




[20] Martin, W.J. (2014) KELEA Activated Water—Enhancing the Alternative Cellular Energy (ACE) Pathway. In: Stealth Adapted Viruses; Alternative Cellular Energy (ACE) & KELEA Activated Water, AuthorHouse In., Bloomington, 115-144.



[21] Emoto, M. (2011) The Hidden Messages in Water. Atria books, New York, 200.



[22] Wells, J.C. (2013) Obesity as Malnutrition: The Dimensions beyond Energy Balance. European Journal of Clinical Nutrition, 67, 507-512.




[23] Batmanghelidj, F. (2008) Your Body’s Many Cries for Water. Global Health Solution, Falls Church, 196.



[24] Martin, W.J. (2014) Stealth Adaptation of Viruses: Review and Updated Molecular Analysis on a Stealth Adapted African Green Monkey Simian Cytomegalovirus (SCMV). Journal of Human Virology & Retrovirology, 1, Article ID: 00020.




[25] Martin, W.J. (2015) Stealth Adaptation of Viruses: Implications for Therapy and for Potential Toxicity of Vaccines. Journal of Virology and Current Research, 1, Article ID: 555551.



[26] Martin, W.J. (2015) Stealth Adapted Viruses. A Bridge between Molecular Virology and Clinical Psychiatry. Open Journal of Psychiatry, 5, 311-319.



[27] Martin, W.J. (2015) Stealth Adapted Viruses—Possible Drivers of Major Neuropsychiatric Illnesses Including Alzheimer’s Disease. Journal of Neurology & Stroke, 2, Article ID: 00057.



[28] Dubrov, V., Dubrova, T., Christner, D., Laurent, D. and Martin, W.J. (2015) Alternative Cellular Energy Based Therapy Using Enercel™ in Advanced AIDS Patients Co-infected with Tuberculosis and Treated in Chernigov, Ukraine. Journal of Human Virology & Retrovirology, 2, Article ID: 00061.



[29] Martin, W.J. and Stoneburner, J. (2014) Alternative Cellular Energy (ACE) Pathway Activation as the Mode of Action of Neutral Red Dye Phototherapy of Human Viruses. Journal of Human Virology & Retrovirology, 1, Article ID: 00019.




[30] Izaguirre, R.R., Guzman, M.R., Fuentes, R.C., Mena, C.E., Penate, E. and Martin, W.J. (2014) Alternative Cellular Energy Based Therapy of Childhood Diarrhea. In: Stealth Adapted Viruses; Alternative Cellular Energy (ACE) & KELEA Activated Water, AuthorHouse In., Bloomington, 103-112.



[31] Dubrov, V., Dubrova, T., Suhareva, V., Christner, D., Baiamonte, J. and Laurent, D. (2012) Efficacy of Treatment with Enercel for New-Onset, Presumed Drug-Sensitive and Confirmed Multidrug Resistant Pulmonary Tuberculosis. USAID/ Ukraine, Tuberculosis, Lung Infections and HIV, 1, 85-91.



[32] Martin, W.J. and Palmer, S.B. (2010) Regenerative Wound Healing Using Copper-Silver Citrate Composition. US Patent Application No. 20100099758.



[33] Liang, S., Christner, D., Du Laux, S. and Laurent, D. (2011) Significant Neurological Improvement in Two Patients with Amyotrophic Lateral Sclerosis after 4 Weeks of Treatment with Acupuncture Injection Point Therapy Using Enercel. Journal of Acupuncture and Meridian Studies, 4, 257-261. http://dx.doi.org/10.1016/j.jams.2011.09.017



[34] Mendelsohn, A.R. and Larrick, J.W. (2013) Sleep Facilitates Clearance of Metabolites from the Brain: Glymphatic Function in Aging and Neurodegenerative Diseases. Rejuvenation Research, 16, 518-523.




[35] Martin, W.J. (2014) KELEA Activated Water Leading to Improved Quantity & Quality of Agricultural Crops. Advances in Plants & Agriculture Research, 2, Article ID: 00033.



[36] Martin, W.J. (2015) Use of Drone to Monitor Enhanced Production of Chlorophyll in Agricultural Crops Resulting From KELEA Activation of Water.





[37] Chaudhary, P., Shank, R.A., Montina, T., Goettel, J.T., Foroud, N.A., Hazendonk, P. and Eudes, F. (2011) Hydrogen-Bonding Interactions in T-2 Toxin Studied Using Solution and Solid-State NMR. Toxins, 3, 1310-1331.




[38] Martin, W.J. (2015) Do the Benefits of Moringa oleifera Trees Extend to KELEA Activation of Water? Advances in Plants & Agriculture Research, 2, Article ID: 00036.




[39] Martin, W.J. (2015) Alternative Cellular Energy. A Unifying Concept in Complementary Alternative Medicine. International Journal Complementary & Alternative Medicine, 1, Article ID: 00022.



[40] Martin, W.J. (2016) Deconstructing Medicine. The Alternative Cellular Energy Pathway. British Journal of Medicine &Medical Research, 11, 1-6.

Indexed for SCIRP by Dragonfly Kingdom Library