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Nature Yogi DJ Producer Designer & Model Marco Andre of Dragonfly Kingdom International Service Agency/Dragonfly Kingdom Library/Underground Intelligence Music & Multimedi

Posted on June 3, 2021 at 9:40 AM Comments comments (0)











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Effect of acute acupuncture treatment on exercise performance and postexercise recovery: a systematic review. - Dragonfly Kingdom Library

Posted on June 3, 2021 at 8:20 AM Comments comments (0)

Abstract

Background: Preliminary evidence suggests that acupuncture applied proximally during a single bout of exercise can enhance exercise performance and/or expedite postexercise recovery. The purpose of this investigation was to review trials, systematically and critically, that have investigated such hypotheses and delineate areas for future research.

 

Method: A systematic review using computerized databases was performed.

 

Results: Four trials were found: Three involved within-subjects designs and one used a parallel group design. Few participants were enrolled (n=10-20). Fourteen acupuncture sites were used across the four trials: DU 20, LI 15, LI 13, PC 6, ST 36, SP 6, PC 5, LU 7, LI 4, GB 37, GB 39, GB 34, and LI 11, and LR 3. PC 6, and ST 36 were the most commonly used sites. Three trials evaluated the effect of acupuncture on exercise performance. One of these trials noted that electroacupuncture stimulation of either PC 5 and PC 6 or LU 7 and LI4 significantly increased peak power output, blood pressure, and rate pressure product (RPP) versus control. However, two trials documented no effect of acupuncture on exercise performance using point combinations of either DU 20, LI 15, LI 13, PC 6, ST 36, and SP 6 or DU 20, ST 36, GB 34, LI 11, LR 3. One trial evaluated the effect of acupuncture on postexercise recovery and found that heart rate, oxygen consumption, and blood lactate were significantly reduced secondary to acupuncturing of PC 6 and ST 36 versus control and placebo conditions at 30 or 60 minutes postexercise.


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Conclusions: There is preliminary support for the use of acupuncture as a means to enhance exercise performance and postexercise recovery, but many limitations exist within this body of literature. Adequately powered, RCTs with thorough and standardized reporting of research methods (e.g., acupuncture and exercise interventions) and results are required to determine more adequately the effect of acupuncture methods on exercise performance and postexercise recovery. Future investigations should involve appropriate placebo methods and blinding of both participants and investigators. 


Indexed for NIH Pubmed by Dragonfly Kingdom Library


https://pubmed.ncbi.nlm.nih.gov/22967279/

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Posted on May 25, 2021 at 8:10 AM Comments comments (0)



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Posted on May 25, 2021 at 7:40 AM Comments comments (0)
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Humming & Breathing Exercises Increase Nasal Nitric Oxide: Harnessing nitric oxide for preventing, limiting and treating the severe pulmonary consequences of COVID-19. - Dragonfly Kingdom Library

Posted on May 20, 2021 at 10:15 AM Comments comments (0)



Harnessing nitric oxide for preventing, limiting and treating the severe pulmonary consequences of COVID-19


https://doi.org/10.1016/j.niox.2020.07.003


Highlights

SARS-CoV-2's pathophysiology is increasingly understood, from entry through ACE2 to the cytokine storm of severe disease.

 

The rapidly growing body of literature identifies several mechanisms that may be targeted with nitric oxide.

 

Reported proofs of concept for inhaled nitric oxide treating COVID-19 demonstrate the need for randomized control trials.



See https://pubmed.ncbi.nlm.nih.gov/12119224/

Humming greatly increases nasal nitric oxide - PubMed




 

 

Abstract

The ongoing outbreak of COVID-19 has quickly become a daunting challenge to global health. In the absence of targeted therapy and a reported 5.5% case fatality rate in the United States, treatments preventing rapid cardiopulmonary failure are urgently needed. Clinical features, pathology and homology to better understood pathogens suggest that uncontrolled inflammation and a cytokine storm likely drive COVID-19's unrelenting disease process. Interventions that are protective against acute lung injury and ARDS can play a critical role for patients and health systems during this pandemic.




Nitric oxide is an antimicrobial and anti-inflammatory molecule with key roles in pulmonary vascular function in the context of viral infections and other pulmonary disease states. This article reviews the rationale for exogenous nitric oxide use for the pathogenesis of COVID-19 and highlights its potential for contributing to better clinical outcomes and alleviating the rapidly rising strain on healthcare capacity........


Indexed for Science Direct by Dragonfly Kingdom Library


https://www.sciencedirect.com/science/article/abs/pii/S1089860320301701?via%3Dihub

Exercise-stimulated glucose uptake - regulation & implications for glycaemic control. - Underground Intelligence Muscle & Fitness/Bright Star Apothecary Harm Reduction Research at Dragonfly Kingdom Library/Dragonfly Kingdom International Service Agency

Posted on May 5, 2021 at 9:15 AM Comments comments (0)

Key Points

Exercise-stimulated signal transduction can restore glucose metabolism in insulin-resistant muscle through both acute activation of glucose transport and by improving insulin sensitivity for up to 48 hours after exercise

Glucose is a major fuel source during exercise and glucose uptake by skeletal muscle can increase by up to 50-fold during bouts of exercise

In excess of 1,000 phosphorylation sites in human skeletal muscle are regulated by exercise, which suggests that many regulators of muscle glucose uptake have yet to be discovered

Regulation of exercise-stimulated glucose uptake by skeletal muscle requires three major steps (delivery, transport and intramyocellular metabolism), any of which could be rate-limiting during various exercise conditions

Intensity and duration of exercise are key determinants of glucose uptake by skeletal muscle

Exercise-stimulated glucose transport is regulated by two major pathways that sense either alterations in the intracellular metabolic milieu (probably mediated by AMPK) or mechanical stress (partly mediated by RAC1)



Abstract


Skeletal muscle extracts glucose from the blood to maintain demand for carbohydrates as an energy source during exercise. Such uptake involves complex molecular signalling processes that are distinct from those activated by insulin. Exercise-stimulated glucose uptake is preserved in insulin-resistant muscle, emphasizing exercise as a therapeutic cornerstone among patients with metabolic diseases such as diabetes mellitus. Exercise increases uptake of glucose by up to 50-fold through the simultaneous stimulation of three key steps: delivery, transport across the muscle membrane and intracellular flux through metabolic processes (glycolysis and glucose oxidation). The available data suggest that no single signal transduction pathway can fully account for the regulation of any of these key steps, owing to redundancy in the signalling pathways that mediate glucose uptake to ensure maintenance of muscle energy supply during physical activity. Here, we review the molecular mechanisms that regulate the movement of glucose from the capillary bed into the muscle cell and discuss what is known about their integrated regulation during exercise. Novel developments within the field of mass spectrometry-based proteomics indicate that the known regulators of glucose uptake are only the tip of the iceberg. Consequently, many exciting discoveries clearly lie ahead.


Indexed for Nature Journal by Dragonfly Kingdom Library

In the Philippine Islands, Peninsular Malaysia, and Andaman Islands, there exist indigenous groups collectively called Negritos whose ancestry can be traced to the รข??First Sundaland People . - Dragonfly Kingdom Library

Posted on May 3, 2021 at 9:35 AM Comments comments (0)

Abstract

Human presence in Southeast Asia dates back to at least 40,000 years ago, when the current islands formed a continental shelf called Sundaland. In the Philippine Islands, Peninsular Malaysia, and Andaman Islands, there exist indigenous groups collectively called Negritos whose ancestry can be traced to the “First Sundaland People.” To understand the relationship between these Negrito groups and their demographic histories, we generated genome-wide single nucleotide polymorphism data in the Philippine Negritos and compared them with existing data from other populations. Phylogenetic tree analyses show that Negritos are basal to other East and Southeast Asians, and that they diverged from West Eurasians at least 38,000 years ago. We also found relatively high traces of Denisovan admixture in the Philippine Negritos, but not in the Malaysian and Andamanese groups, suggesting independent introgression and/or parallel losses involving Denisovan introgressed regions. Shared genetic loci between all three Negrito groups could be related to skin pigmentation, height, facial morphology and malarial resistance. These results show the unique status of Negrito groups as descended from the First Sundaland People.


Indexed for Academic OUP 


https://academic.oup.com/gbe/article/9/8/2013/3952725





Clinical study to evaluate the efficacy of Ayurvedic Herbal Formulation for Obesity in overweight individuals. - Bright Star Apothecary/Underground Intelligence Muscle & Fitness at Dragonfly Kingdom Library/Dragonfly Kingdom International Service Agency

Posted on May 3, 2021 at 12:55 AM Comments comments (0)

A clinical study to evaluate the efficacy of Herbal Formulation for Obesity (HFO-02) in overweight individuals



Under a Creative Commons license

Abstract

Background

Ayurveda, the Indian system of medicine offers many herbs and formulations for management of obesity. Baidyanath Bhawan Pvt. Ltd has designed a formulation, HFO-02, based on Ayurvedic literature.

 

Objective

To evaluate the efficacy of Herbal Formulation for Obesity (HFO-02) in overweight individuals.

 

Materials & methods

With approval from the Institutional Ethics Committee, a proof of concept study was carried out in overweight individuals (Body Mass Index, BMI ≥25.0 and ≤ 30.0 kg/m2), devoid of any endocrinological disorders. Tablet HFO-02 (500 mg) was administered to these individuals twice daily for 90 days, during which they were called at study site fortnightly. After stopping the treatment, they were further followed up for 30 days off-medication and the last follow up was scheduled on day 120. Anthropometric parameters were assessed at every visit, while biochemical parameters viz. lipid profile, blood sugar & insulin levels (both fasting and post prandial), C- reactive protein and adipocytokines (leptin & adiponectin) were estimated monthly.


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Results

Of the 18 participants recruited in the study; 14 completed the study. HFO-02 did not show reduction in weight, however a significant decrease in the body circumference and skin fold was demonstrated. This decrease was maintained till day 120. The levels of all biochemical parameters were maintained and no adverse events were reported throughout the study.

 

Conclusion

Tablet HFO-02 reduced body circumferences and skinfold thickness indicating its potential for obesity management.

 

Clinical trial registration number

CTRI/2016/07/007067



Indexed for Science Direct by Dragonfly Kingdom Library


https://www.sciencedirect.com/science/article/pii/S0975947618310441#bib4

High protein diets decrease total and abdominal fat and improve CVD risk profile in overweight and obese men and women with elevated triacylglycerol. - Dragonfly Kingdom Library

Posted on May 2, 2021 at 11:10 AM Comments comments (0)

Abstract

Background and aims: It is unclear whether high protein weight loss diets have beneficial effects on weight loss, abdominal fat mass, lipids, glucose and insulin compared to conventional low fat diets in subjects at increased risk of cardiovascular disease (CVD) because of elevated glucose and triglyceride concentrations. Our objective was to determine the effects of high protein (HP) compared to standard protein (SP) diets on CVD risk in obese adults.

 

Methods and results: Data from three, 12 week, randomized parallel trials with subjects assigned to either HP or SP diet (5500-6500 kJ/day) were pooled. Weight, body composition (dual energy X-ray absorptiometry), lipids, insulin and glucose were measured before and after weight loss. Data from 215 subjects (49.9+/-9.8 years, BMI 33.5+/-3.7 kg/m(2)), 108 HP, 107 SP were analyzed. Weight loss (HP diet 7.82+/-0.37 kg; SP diet 7.65+/-0.39 kg, NS) and total fat loss were not different (HP 6.8+/-4.3 kg; LP 6.4+/-4.7 kg, NS on intention to treat analysis). The reduction in triacylglycerol (TAG) was greater on HP than SP 0.48+/-0.07 mmol/L vs 0.27+/-0.06 mmol/L, (P<0.001). Subjects with TAG greater than the median (>1.54 mmol/L at baseline) lost more weight (HP 8.5+/-0.6; SP 6.9+/-0.6 kg, P=0.01, diet by TG group), total (HP 6.17+/-0.50 kg; SP 4.52+/-0.52 kg, P=0.007) and abdominal fat (HP 1.92+/-0.17 kg; SP 1.23+/-0.19 kg, P=0.005) on HP. Total cholesterol (12 vs 6%, HP vs SP) and TAG (39 vs 20%, HP vs SP) decreased to a greater extent in these subjects 


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Conclusion: Short-term high protein weight loss diets had beneficial effects on total cholesterol and triacylglycerol in overweight and obese subjects and achieved greater weight loss and better lipid results in subjects at increased risk of CVD. These observations provide further information regarding the utility of this dietary approach in effectively managing body weight and composition and reducing CVD risk in overweight and obese individuals 


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Indexed for NIH Pubmed by Dragonfly Kingdom Library 


https://pubmed.ncbi.nlm.nih.gov/19179060/





A Review of Exercise as Medicine in Cardiovascular Disease: Pathology and Mechanism. - Dragonfly Kingdom Library/Dragonfly Kingdom International Service Agency

Posted on May 1, 2021 at 10:45 AM Comments comments (0)

Abstract

Background

Physical inactivity and resultant lower energy expenditure contribute unequivocally to cardiovascular diseases, such as coronary artery disease and stroke, which are considered major causes of disability and mortality worldwide.

 

Aim

The aim of the study was to investigate the influence of physical activity (PA) and exercise on different aspects of health - genetics, endothelium function, blood pressure, lipid concentrations, glucose intolerance, thrombosis, and self - satisfaction.

 

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Materials and Methods

In this article, we conducted a narrative review of the influence PA and exercise have on the cardiovascular system, risk factors of cardiovascular diseases, searching the online databases; Web of Science, PubMed and Google Scholar, and, subsequently, discuss possible mechanisms of this action.

 

Results and Discussion

Based on our narrative review of literature, discussed the effects of PA on telomere length, nitric oxide synthesis, thrombosis risk, blood pressure, serum glucose, cholesterol and triglycerides levels, and indicated possible mechanisms by which physical training may lead to improvement in chronic cardiovascular diseases.

 

Conclusion

PA is effective for the improvement of exercise tolerance, lipid concentrations, blood pressure, it may also reduce the serum glucose level and risk of thrombosis, thus should be advocated concomitant to, or in some cases instead of, traditional drug-therapy.

 

Keywords: physical activity, longevity, cardiovascular disease, public health problem, aging 


Indexed for NIH by Dragonfly Kingdom Library 


https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069454/



Music intervention using percussion instruments with familiar music as a cost-effective approach has the potential to reduce anxiety and improve psychological well-being of those with dementia. - Dragonfly Kingdom Library

Posted on April 28, 2021 at 7:20 AM Comments comments (0)

Abstract

Objective: This experimental study aimed to evaluate the effects of a group music intervention on anxiety and agitation of institutionalized older adults with dementia.

 

Methods: A total of 60 participants were randomly assigned to an experimental or a control group. The experimental group received a 30-min music intervention using percussion instruments with familiar music in a group setting in mid afternoon twice weekly for 6 weeks, whereas the control group received usual care with no music intervention. The Rating of Anxiety in Dementia scale was used to assess anxiety, and Cohen-Mansfield Agitation Inventory was used to assess agitation at baseline, week 4 and week 6.

 

Results: Repeated measures analysis of covariance indicated that older adults who received a group music intervention had a significantly lower anxiety score than those in the control group while controlling for pre-test score and cognitive level (F = 8.98, p = 0.004). However, the reduction of agitation between two groups was not significantly different.

 

Conclusions: Anxiety and agitation are common in older adults with dementia and have been reported by caregivers as challenging care problems. An innovative group music intervention using percussion instruments with familiar music as a cost-effective approach has the potential to reduce anxiety and improve psychological well-being of those with dementia.


Indexed for NIH Pubmed by Dragonfly Kingdom Library


https://pubmed.ncbi.nlm.nih.gov/21823174/

Adopting yoga/meditation-based lifestyle modification causes reversal of markers of aging, mainly oxidative stress, telomerase activity, and oxidative DNA damage. - Dragonfly Kingdom Library

Posted on April 28, 2021 at 7:15 AM Comments comments (1)

Abstract

Objectives: Recent studies showed that a brief yoga-based lifestyle intervention was efficacious in reducing levels of oxidative stress and cellular aging in obese men. The objective of this case report was to assess the efficacy of this intervention in reducing the levels of biochemical markers of cellular ageing, oxidative stress, and inflammation at baseline (day 0), at the end of active intervention (day 10), and follow-up at day 90.

 

Design: Single case report from a prospective ongoing study with pre-post design assessing the level of various markers of cellular aging.

 

Setting: Integral Health Clinic, an outpatient facility conducting meditation and yoga-based lifestyle intervention programs for management of chronic diseases.

 

Patient: A 31-year-old man with class I obesity (body-mass index, 29.5 kg/m(2)) who presented to the medicine outpatient department at All India Institute of Medical Sciences, New Delhi, India, with a history of fatigue, difficulty losing weight, and lack of motivation. He noted a marked decrease in his energy level, particularly in the afternoon.

 

Intervention: A pretested intervention program included asanas (postures), pranayama (breathing exercises), stress management, group discussions, lectures, and individualized advice.

 

Results: From baseline (day 0) to day 90, the activity of telomerase and levels of β-endorphins, plasma cortisol, and interleukin-6 increased, and a sustained reduction in oxidative stress markers, such as reactive oxygen species and 8-hydroxy-2-deoxy-guanosine levels.

 

Conclusions: Adopting yoga/meditation-based lifestyle modification causes reversal of markers of aging, mainly oxidative stress, telomerase activity, and oxidative DNA damage. This may not only delay aging and prolong a youthful healthy life but also delay or prevent onset of several lifestyle-related diseases, of which oxidative stress and inflammation are the chief cause. This report suggests this simple lifestyle intervention may be therapeutic for oxidative DNA damage and oxidative stress.


Indexed for NIH Pubmed by Dragonfly Kingdom Library


https://pubmed.ncbi.nlm.nih.gov/25964984/

A two-year follow-up case of chronic fatigue syndrome: substantial improvement in personality following a yoga-based lifestyle intervention. - Dragonfly Kingdom Library

Posted on April 28, 2021 at 7:10 AM Comments comments (0)

Abstract

Background and objective: Chronic Fatigue Syndrome (CFS) is characterized by excessive fatigue after minimal physical or mental exertion, muscle and joint pain, poor concentration, dizziness, and sleep disturbances. We report here the effect of a yoga-based lifestyle intervention in a 30-year old male patient with a documented diagnosis of CFS with compromised quality of life (QoL) and altered personality.

 

Methods: The patient initially attended a short-term yoga-based lifestyle intervention program that consisted of yoga-postures, breathing exercises (pranayama), meditation, group discussions, and individualized advice on stress management, diet and physical activity besides group support. Thereafter, patient attended 5 more such programs.

 

Results: There was a notable and consistent improvement in his clinical profile, positive aspects of personality and subjective well-being, and reduction in anxiety following this yoga-based lifestyle intervention.

 

Conclusion: Overall, the results suggest that lifestyle intervention may improve clinical condition and personality in patients with CFS.


Indexed for NIH Pubmed by Dragonfly Kingdom Library


https://pubmed.ncbi.nlm.nih.gov/25825998/

Medical Yoga Therapy. - Dragonfly Kingdom Library/Bright Star Apothecary/Marco's Fitness Travel & Adventures

Posted on April 28, 2021 at 7:05 AM Comments comments (0)

Abstract

Medical yoga is defined as the use of yoga practices for the prevention and treatment of medical conditions. Beyond the physical elements of yoga, which are important and effective for strengthening the body, medical yoga also incorporates appropriate breathing techniques, mindfulness, and meditation in order to achieve the maximum benefits. Multiple studies have shown that yoga can positively impact the body in many ways, including helping to regulate blood glucose levels, improve musculoskeletal ailments and keeping the cardiovascular system in tune. It also has been shown to have important psychological benefits, as the practice of yoga can help to increase mental energy and positive feelings, and decrease negative feelings of aggressiveness, depression and anxiety.

 

Keywords: yoga, yogic practice, anxiety, depression, mindfulness, meditation, arthritis, ADHD, cardiovascular disease, inflammation

1. Introduction

Within the past decade, yoga has infiltrated not only Western culture, but also Western medicine. The more we learn about this ancient practice, the more we realize that its benefits go far beyond increased flexibility and muscle tone. A common misunderstanding is that yoga predominantly focuses on increasing flexibility; however, although Hatha Yoga, or the physical practice of yoga, does emphasize appropriate postural alignment, musculoskeletal strength and endurance as well as balance, the study and practice of yoga incorporates mindfulness-based practices such as mindful breathing techniques, focused concentration, meditation and self-reflection.

 

Modern medicine has made enormous progress in controlling communicable diseases over the past century, such that it is now the non-communicable diseases (NCDs) that have reached epidemic proportions and cause the majority of deaths worldwide. The World Health Organization (WHO) estimates that 80% of NCD deaths are due to four main disease types: cardiovascular disease, cancer, diabetes, and respiratory diseases [1]. Unfortunately, lifestyle is the major causative factor in NCDs, including tobacco use, sedentary lifestyle, lack of regular exercise, unhealthy diets and chronic psychosocial stress [1,2]. Chronic inflammation and stress is a common factor of many of the NCDs, and an area where yoga has been found to be extremely beneficial.

 

Recent research has shown that yogic and mindfulness-based practices can positively impact the body in many ways, including helping to regulate blood glucose levels and keeping the cardiovascular system healthy. It also has been shown to have important psychological benefits, as the practice of yoga can help to increase alertness and positive feelings, and decrease negative feelings of aggressiveness, depression and anxiety.......


Indexed for NIH by Dragonfly Kingdom Library


Full article at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332914/#!po=1.10410