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Exercise Strategy, Fitness As Detox: Arsenic, Cadmium, Lead, and Mercury in Sweat. -- Underground Intelligence Muscle & Fitness

Posted on March 13, 2022 at 5:40 AM

Arsenic, Cadmium, Lead, and Mercury in Sweat: A Systematic Review

Margaret E. Sears, Kathleen J. Kerr, and Riina I. Bray




Arsenic, cadmium, lead, and mercury exposures are ubiquitous. These toxic elements have no physiological benefits, engendering interest in minimizing body burden. The physiological process of sweating has long been regarded as “cleansing” and of low risk. Reports of toxicant levels in sweat were sought in Medline, Embase, Toxline, Biosis, and AMED as well as reference lists and grey literature, from inception to March 22, 2011. Of 122 records identified, 24 were included in evidence synthesis.

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Populations, and sweat collection methods and concentrations varied widely. In individuals with higher exposure or body burden, sweat generally exceeded plasma or urine concentrations, and dermal could match or surpass urinary daily excretion. Arsenic dermal excretion was severalfold higher in arsenic-exposed individuals than in unexposed controls. Cadmium was more concentrated in sweat than in blood plasma. Sweat lead was associated with high-molecular-weight molecules, and in an interventional study, levels were higher with endurance compared with intensive exercise. Mercury levels normalized with repeated saunas in a case report. Sweating deserves consideration for toxic element detoxification. Research including appropriately sized trials is needed to establish safe, effective therapeutic protocols.


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1. Introduction

No person is without some level of toxic metals in their bodies, circulating and accumulating with acute and chronic lifetime exposures. An individual may take numerous measures to minimize exposures and to optimize metabolism and excretion of toxic elements in the stool and urine with diet, supplements, and chelation therapy [1, 2]; however, an often overlooked route of excretion of toxicants is via the process of sweating [3].


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Sweating with heat and/or exercise has been viewed throughout the ages, by groups worldwide, as “cleansing.” As part of a scoping review regarding arsenic, cadmium, lead, and mercury, we reviewed the scientific literature pertaining to toxicant excretion in sweat.........

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